Mediterranean Diet With Optional Cycling and Rowing to Improve Blood Sugar in Women with Prediabetes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study investigates how a Mediterranean-style diet, alone or paired with supervised cycling and rowing exercises, affects daily blood sugar control in women with prediabetes. Participants are assigned to three groups based on current blood sugar: diet only, diet plus exercise with high blood sugar, and a group with diet plus exercise if currently in normal range. The trial uses continuous glucose monitoring to capture daily glycemic variability in addition to standard tests. The aim is to see if adding structured exercise to the Mediterranean diet improves glycemic control more than diet alone, and whether responders differ by initial glycemic status. The study emphasizes lifestyle modification as a means to reduce progression toward type 2 diabetes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Having a diagnosis of prediabetes (within the last 1 year)

  * Impaired Fasting Glucose (IFG) 100-125 mg/dl
  * OGTT result 2-hour postprandial Impaired Glucose Tolerance (IGT) 140-199 mg/dl
  * HbA1c 5.7-6.4%
* Being between 22-55 years of age
* Being female
* Body Mass Index 18-34.9 kg/m2
* Meeting the criteria in the American College of Sports Medicine (ACSM) and American Heart Association (AHA) cardiovascular disease risk assessment scoring system
* Not engaging in regular planned exercise or physical activity (sedentary)

Exclusion Criteria:

* Diabetes
* Being pregnant
* No self-reported low iron concentrations or anaemia
* Use of medication, insulin, or weight loss injections known to affect lipid and glucose metabolism
* Presence of cardiovascular disease
* Current smoking or excessive alcohol consumption
* Presence of abnormal electrocardiogram (ECG)
* Presence of autonomic neuropathy
* Presence of uncontrolled hypertension (systolic blood pressure \>135 mmHg, diastolic blood pressure \>85 mmHg)
* Joint-muscle-bone injury limiting exercise

Where it's running

• Marmara University
  Beykoz, Istanbul, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Begüm Yücesoy Güneysu, PhD (c)
• Email: begum.yucesoy@gmail.com
• Phone: +90-5377964919

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.