Mechanical ventilation in adults during surgery
Official title: Management of Mechanical Ventilation During Surgery: an International, Multicenter, and Observational Data Registry
Run by Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria · NCT06296277 · Data updated 2026-11-12
This study tests how often postoperative lung problems occur in adults who are ventilated during general anesthesia for surgery and explores how ventilation practices relate to those problems.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 10000 (estimated) |
| Sponsor | Azienda Ospedaliera SS. Antonio e Biagio e Cesare Arrigo di Alessandria Academic / other |
| Locations | 1 site (Alessandria, Italy) |
| Status | Recruiting |
| Started | March 1, 2026 |
| Main results expected | August 31, 2027 |
| Study ends | August 31, 2027 |
| Registry record updated | May 28, 2026 |
| Trial ID | NCT06296277 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults undergoing general anesthesia who require intraoperative mechanical ventilation via endotracheal tube or supraglottic device.
✕Probably not a fit
Patients not expected to benefit are those not receiving intraoperative ventilation or those excluded (e.g., ventilation outside the operating room or during extracorporeal life support).
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an investigator-initiated, international, multicenter, prospective, cross-sectional study of adults receiving intraoperative mechanical ventilation during general anesthesia for surgery. It aims to describe the incidence and types of postoperative pulmonary complications within the first 5 days after surgery, along with patient demographics, baseline characteristics, and intraoperative ventilation management. Additional goals include documenting intraoperative adverse events, their associations with PPCs, and analyzing how intraoperative ventilation is practiced across participating centers. Secondary endpoints cover other postoperative complications, ICU and hospital length of stay, and 28-day mortality. Hospitals can select their data collection window to capture a representative snapshot of current practice.
Why it matters
Potential benefit: If successful, the study could clarify how intraoperative ventilation relates to PPCs and other outcomes, informing future guidelines and practice improvements.
How similar studies have gone: Previous observational work has explored intraoperative practices and PPCs, but this study adds a multicenter, international perspective focused on associations with ventilation management.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults; and * Receiving intraoperative IMV (via tracheal intubation, or supraglottic device ) during general anesthesia for surgery Exclusion Criteria: * Receiving intraoperative IMV outside of an operating room; and * Receiving intraoperative IMV during extracorporeal life support
Where it's running
-
Azienda Ospedaliero Universitaria di Alessandria
Alessandria, Italy, Italy Recruiting
Study contacts
- Principal investigator: Gianmaria Cammarota, Prof — Università degli Studi del Piemonte Orientale
- Study coordinator: Gianmaria Cammarota, Prof
- Email: gianmaria.cammarota@uniupo.it
- Phone: +393213733406
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.