Managing GERD with personalized dietary changes and guided education
Official title: Comprehensive Management Strategies for Gastroesophageal Reflux Disease: A Study of Multidimensional Interventions and Health Impacts
Run by Hualien Tzu Chi General Hospital · NCT07754721 · Data updated 2026-11-12
A dietary plan and written education are being tested to see if they help adults with chronic GERD reduce symptoms.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 79 Years |
| Sex | All |
| Enrollment | 220 (estimated) |
| Sponsor | Hualien Tzu Chi General Hospital Academic / other |
| Locations | 1 site (Hualien City, Taiwan) |
| Status | Recruiting |
| Started | January 2, 2025 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | September 10, 2026 |
| Trial ID | NCT07754721 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18-79 with chronic GERD symptoms willing to modify their diet.
✕Probably not a fit
Individuals with specific esophageal disorders or certain medications may not benefit from dietary changes alone.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study examines whether individualized nutrition guidance and written dietary education can improve GERD symptoms. Participants will receive guidance from a nutritionist and written materials to help adjust meals and timing. The goal is to see if targeted dietary changes reduce nighttime reflux and related symptoms. The study excludes people with certain esophageal conditions or on medications that affect esophageal motility. Results could inform practical dietary strategies for GERD management.
Why it matters
Potential benefit: If successful, participants may experience fewer reflux symptoms and better sleep and quality of life.
How similar studies have gone: Dietary approaches for GERD have shown promise, but robust randomized data are limited; this study adds structured nutrition guidance.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Aged 18-79 years, mentally alert, and willing to provide written informed consent. 2. Individuals with chronic gastroesophageal reflux symptoms (acid regurgitation, chest pain, or heartburn) who are willing to undergo dietary intervention. Exclusion Criteria: 1. Individuals with esophageal stricture, current or prior diagnosis of esophageal tumors, or a history of esophageal, upper gastrointestinal, or pharyngeal surgery. 2. Individuals with structural esophageal disorders (e.g., diverticulum, esophageal rings), infectious esophagitis, or eosinophilic esophagitis. 3. Individuals with major esophageal motility disorders. 4. Individuals taking medications that may affect esophageal motility (e.g., opioids, nitrates, calcium channel blockers). 5. Individuals who have used antidepressants, selective serotonin reuptake inhibitors (SSRIs), or other psychiatric medications continuously within the past three months, or are currently taking them. 6. Pregnant women, or individuals unable to comply with lifestyle and dietary interventions for other reasons.
Where it's running
-
Hualien Tzu Chi Hospital,Buddhist Tzu Chi Medical Foundation
Hualien City, Taiwan, Taiwan Recruiting
Study contacts
- Study coordinator: Wei-Yi Lei Gastroenterology attending physician
- Email: hlmweb@tzuchi.com.tw
- Phone: +88638561825
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.