GERD patient registry study using a large prospective clinical database
Official title: Establishing an Innovative Cohort of Chinese Patients With Gastroesophageal Reflux Disease Based on the Prospective Database of the National Clinical Research Center for Digestive Diseases: A Retrospective Study
Run by Beijing Friendship Hospital · NCT07749989 · Data updated 2026-11-12
A large group of adults with gastroesophageal reflux disease are being looked at in real-world care to see who they are, what treatments they get, and how symptoms and well-being change after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Beijing Friendship Hospital Academic / other |
| Locations | 1 site (Beijing, Beijing Municipality) |
| Status | Recruiting |
| Started | April 17, 2026 |
| Main results expected | April 2027 |
| Study ends | May 2027 |
| Registry record updated | August 6, 2026 |
| Trial ID | NCT07749989 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18 to 90 with a confirmed GERD diagnosis who were evaluated and treated at Beijing Friendship Hospital and consent to use of their data.
✕Probably not a fit
Patients with incomplete data, uncertain GERD diagnosis, or those who do not consent may not benefit from the study findings.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational analysis using data from a prospective registry to describe demographics, clinical features, psychological status, and treatment patterns of GERD patients in China. Researchers will retrospectively extract baseline and follow-up data, including diagnostic findings, preoperative psychology, surgical outcomes, and symptom changes after treatment. The goal is to understand real-world care and post-treatment quality of life in a large cohort. The study leverages data from Beijing Friendship Hospital and uses clinical information for future research.
Why it matters
Potential benefit: If successful, insights could inform patient care pathways and improve understanding of how treatments affect GERD symptoms and psychological well-being in real-world settings.
How similar studies have gone: Previous real-world data analyses of GERD have provided meaningful insights into treatment patterns and outcomes, supporting the value of this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged between 18 and 90 years old. * Patients were required to present with at least one typical symptom of gastroesophageal reflux disease (GERD)-such as heartburn, regurgitation, or non-cardiac chest pain-and to have presented to Beijing Friendship Hospital for the evaluation and management of these symptoms. * Received treatment, including pharmacological therapy and anti-reflux surgery, at Beijing Friendship Hospital. * Voluntary signing of informed consent, agreeing to the use of clinical information for future research. Exclusion Criteria: * Female patients who were pregnant or lactating. * Patients with significantly incomplete or missing critical clinical data. * Patients with an equivocal or unconfirmed diagnosis of GERD. * Current neurologic or cognitive impairment, which would preclude ability to obtain informed consent. * Refusal to participate in the study.
Where it's running
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Beijing Friendship Hospital, Capital Medical University
Beijing, Beijing Municipality, China Recruiting
Study contacts
- Study coordinator: Zhi Zheng, Attending surgon
- Email: zhengzhi@ccmu.edu.cn
- Phone: +86-13811132175
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Predictors of symptom improvement after laparoscopic fundoplication
This study tests what preoperative factors help predict which GERD patients will feel better after laparoscopic fundoplication.
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Thread-Embedding Acupuncture plus a Proton Pump Inhibitor for GERD
This study tests whether adding thread-embedding acupuncture to standard omeprazole treatment helps people with GERD who have a traditional Liver-Stomach constraint-heat pattern.
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Managing GERD with personalized dietary changes and guided education
A dietary plan and written education are being tested to see if they help adults with chronic GERD reduce symptoms.
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Mindfulness Intervention for Emotional Distress in GERD
This online mindfulness program is being tested to see if it can help adults with GERD feel less emotional distress and experience fewer reflux symptoms.
-
Comparing two medications for treating gastroesophageal reflux disease symptoms
This study is testing whether tegoprazan works better than pantoprazole in helping adults with gastroesophageal reflux disease (GERD) feel better after four weeks of treatment.
-
A new surgical approach to reduce GERD after weight loss surgery
This study is testing a new type of weight loss surgery to see if it can help reduce acid reflux in people who have had weight loss surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.