Online ACT for Disorders of Gut-Brain Interaction: See if it helps you cope
Official title: Efficacy, and Cost-effectiveness of an Online ACT Intervention for Disorders of Gut-Brain Interaction (iACTforDGBI)
Run by Örebro University, Sweden · NCT07814196 · Data updated 2026-11-12
This online program tests whether the iACTforDGBI program helps people with gut-brain disorders who are feeling distress, compared with an active control called DGBI School.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 75 Years |
| Sex | All |
| Enrollment | 200 (estimated) |
| Sponsor | Örebro University, Sweden Academic / other |
| Locations | 1 site (Örebro) |
| Status | Recruiting |
| Started | September 15, 2026 |
| Main results expected | September 30, 2027 |
| Study ends | September 30, 2027 |
| Registry record updated | October 23, 2026 |
| Trial ID | NCT07814196 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–75 with at least one DGBI diagnosis and stable psychiatric symptoms who can read Swedish and access internet-enabled devices for video sessions.
✕Probably not a fit
Individuals without DGBI symptoms, with unstable psychiatric treatment, or without reliable internet access may not benefit from this intervention.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study compares an online ACT-based program for disorders of gut-brain interaction with an active control. Adults aged 18 to 75 with at least one DGBI diagnosis and stable psychiatric medication participate in a randomized or controlled design to test efficacy and cost-effectiveness. Participants must have internet access, be able to read Swedish, and can attend video sessions. Exclusions include active psychological treatment for other conditions, high suicide risk, or certain severe psychiatric disorders. The primary aim is to determine whether iACTforDGBI improves symptoms and is cost-effective relative to the DGBI School program.
Why it matters
Potential benefit: If successful, participants may experience improved GI-related symptoms and distress, with evidence on whether the online program provides good value for care.
How similar studies have gone: Previous ACT-based approaches for functional GI disorders have shown promising results, though online delivery and cost-effectiveness data in this specific DGBI population are still being established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 75 years * Meeting clinical symptom levels for least one DGBI diagnosis (assessed with the Rome IV Diagnostic Questionnaire for Functional Gastrointestinal Disorders in Adults (Palsson et al., 2016)) * Stable medication for psychiatric symptoms including anxiety, depression and sleep problems for at least two months prior to intervention. * Ability to read and write Swedish * Have access to a device (like computer, tablet or smartphone with) with access to the internet and that can be used to attend video conferences and preview the intervention platform (i.e., have a microphone and speakers or headphones). Exclusion Criteria: * Currently undergoing any form of psychological intervention. * Increased risk of suicide (≥4 points on MADRS item 9). * Ongoing or previously diagnosed severe psychiatric disorder, such as schizophrenia spectrum disorders or bipolar disorder.
Where it's running
-
Örebro University
Örebro, Sweden Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Noninvasive test to measure small bowel sensation using mannitol distension
A noninvasive test using different concentrations of mannitol solution is tried in healthy people to see how their small bowel feels distension.
-
Transauricular Neurostimulation for Abdominal Pain in Teens
We are testing a head- and ear‑based device to see if it helps teens with abdominal pain from gut-brain disorders.
-
Managing GERD with personalized dietary changes and guided education
A dietary plan and written education are being tested to see if they help adults with chronic GERD reduce symptoms.
-
Acupuncture for pediatric disorders of gut–brain interaction
This trial will test whether acupuncture can reduce symptoms in children and teens (ages 8–17) with disorders of gut–brain interaction.
-
WHO psychological programs to support mental health in migrants resettled in Italy (ADVANCE)
This project will see if WHO's Self-Help Plus (SH+) and Doing What Matters (DWM) programs reduce anxiety and depression in migrants living in Italy who have elevated psychological distress.
-
Integrative yoga and mindful self‑compassion for women with past interpersonal violence and distress
This trial will test whether a 12-week integrative yoga and mindful self-compassion program helps women aged 18–65 with a history of interpersonal violence and elevated distress compared with a women's wellbeing education program.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.