Clinical trial Recruiting at 1 site Interventional Ages 18 to 80

Analgesia after open inguinal hernia repair using intrathecal morphine or a transversalis fascia plane block

Official title: Comparison of Intrathecal Morphine, Transversalis Fascia Plane Block, and Spinal Anesthesia Alone for Postoperative Analgesia in Open Inguinal Hernia Repair: A Prospective, Randomized, Assessor-Blinded, Controlled Trial

Run by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · NCT07826741 · Data updated 2026-11-12

This trial tests whether intrathecal morphine or a ultrasound-guided transversalis fascia plane block can provide better pain relief after open inguinal hernia repair in adults.

Quick facts

Study typeInterventional
Ages18 Years to 80 Years
SexAll
Enrollment90 (estimated)
SponsorAtatürk Chest Diseases and Chest Surgery Training and Research Hospital
Academic / other
Locations1 site (Yenimahalle, Ankara)
StatusRecruiting
StartedSeptember 18, 2026
Main results expectedApril 10, 2027
Study endsApril 25, 2027
Registry record updatedSeptember 21, 2026
Trial IDNCT07826741 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–80 years undergoing elective open inguinal hernia repair, with ASA I–III and BMI 18–30 kg/m².

Probably not a fit

Patients who do not respond to regional techniques or have contraindications to neuraxial anesthesia may not experience benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults undergoing open inguinal hernia repair are randomized to receive intrathecal morphine, a transversalis fascia plane block, or standard care. The study uses assessor blinding to compare postoperative pain, opioid use, and recovery metrics. It aims to determine if regional or neuraxial analgesia can reduce opioid requirements and improve comfort after surgery. Safety will be monitored for known opioid-related adverse effects and block-related complications. The trial is conducted at Ankara Etlik City Hospital with a single lead sponsor in Turkey.

Why it matters

Potential benefit: If successful, patients could experience better pain control with fewer opioid needs after surgery.

How similar studies have gone: Regional anesthesia and neuraxial techniques have shown pain relief in similar surgeries, but direct comparisons in this exact setup are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age between 18 and 80 years
* American Society of Anesthesiologists physical status I-II-III
* Body mass index between 18 and 30 kg/m²
* Patients undergoing elective open inguinal hernia repair

Exclusion Criteria:

* Patient refusing the procedure
* History of chronic analgesic or opioid therapy
* History of local anesthetic and morphine allergy
* Infection in the intervention area

Where it's running

  • Ankara Etlik City Hospital
    Yenimahalle, Ankara, Turkey (Türkiye)
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.