Analgesia after open inguinal hernia repair using intrathecal morphine or a transversalis fascia plane block
Official title: Comparison of Intrathecal Morphine, Transversalis Fascia Plane Block, and Spinal Anesthesia Alone for Postoperative Analgesia in Open Inguinal Hernia Repair: A Prospective, Randomized, Assessor-Blinded, Controlled Trial
Run by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · NCT07826741 · Data updated 2026-11-12
This trial tests whether intrathecal morphine or a ultrasound-guided transversalis fascia plane block can provide better pain relief after open inguinal hernia repair in adults.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 80 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | Atatürk Chest Diseases and Chest Surgery Training and Research Hospital Academic / other |
| Locations | 1 site (Yenimahalle, Ankara) |
| Status | Recruiting |
| Started | September 18, 2026 |
| Main results expected | April 10, 2027 |
| Study ends | April 25, 2027 |
| Registry record updated | September 21, 2026 |
| Trial ID | NCT07826741 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults aged 18–80 years undergoing elective open inguinal hernia repair, with ASA I–III and BMI 18–30 kg/m².
✕Probably not a fit
Patients who do not respond to regional techniques or have contraindications to neuraxial anesthesia may not experience benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Adults undergoing open inguinal hernia repair are randomized to receive intrathecal morphine, a transversalis fascia plane block, or standard care. The study uses assessor blinding to compare postoperative pain, opioid use, and recovery metrics. It aims to determine if regional or neuraxial analgesia can reduce opioid requirements and improve comfort after surgery. Safety will be monitored for known opioid-related adverse effects and block-related complications. The trial is conducted at Ankara Etlik City Hospital with a single lead sponsor in Turkey.
Why it matters
Potential benefit: If successful, patients could experience better pain control with fewer opioid needs after surgery.
How similar studies have gone: Regional anesthesia and neuraxial techniques have shown pain relief in similar surgeries, but direct comparisons in this exact setup are limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age between 18 and 80 years * American Society of Anesthesiologists physical status I-II-III * Body mass index between 18 and 30 kg/m² * Patients undergoing elective open inguinal hernia repair Exclusion Criteria: * Patient refusing the procedure * History of chronic analgesic or opioid therapy * History of local anesthetic and morphine allergy * Infection in the intervention area
Where it's running
-
Ankara Etlik City Hospital
Yenimahalle, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Study coordinator: Musa Zengin, Associate Professor
- Email: musazengin@gmail.com
- Phone: 00905307716235
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.