Low-load blood flow restriction versus high-load eccentric training for muscle changes and knee injury prevention in young athletes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, three-arm interventional trial will assign competitive young athletes to low-load blood flow restriction (LL-BFRt), a sham LL-BFRt, or high-load eccentric training (HL-Et). The LL-BFRt group performs eccentric exercises (stairs, single-leg squat, single-leg deadlift) at about 30% of repetition maximum with cuff pressure at ~70% of arterial occlusion pressure, the HL-Et group performs eccentric work at ~70% RM, and the sham group performs low-load work without true occlusion. Primary outcomes focus on changes in muscle morphology and markers related to prevention of patellofemoral pain syndrome and ACL injury. Sessions are conducted at the physical therapy laboratory of Universitas Udayana and a partnering physiotherapy clinic in Denpasar, Bali.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Being between the ages of 15 and 35
* Play level 1 sports (fight martial arts, basketball, futsal, and soccer) at least twice a week
* Never experienced an Patellofemoral Pain Syndrome or ACL injury before
* Never experienced a grade III sprain or strain
* Consent to participate in the study until its conclusion and provide informed consent.

Exclusion Criteria:

* Having a tumor, cancer, vena thromboembolic disease, obesity, diabetes, hypertension, anemia, and renal failure
* Disabilities or those who are disabled.

Where it's running

• Physical therapy laboratory, College of Medicine, Universitas Udayana and ROM Physiotherapy Private Clinic Denpasar
  Denpasar, Bali, Indonesia Recruiting

Study contacts

• Study coordinator: I Putu Gde Surya Adhitya, PhD
• Email: surya_adhitya@unud.ac.id
• Phone: +6288975003567

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.