Perturbation Training vs Functional Activities after ACL Reconstruction
Official title: Effects of Perturbation Training Versus Task-oriented Functional Activities on Pain, Range of Motion, Balance and Function in Post-anterior Cruciate Ligament Reconstruction
Run by Riphah International University · NCT07642752 · Data updated 2026-11-12
This study tests whether perturbation training or task-oriented functional activities help people 18–45 with ACL reconstruction recover better than standard rehab.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 45 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | Riphah International University Academic / other |
| Locations | 1 site (Lahore, Punjab Province) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | November 15, 2026 |
| Study ends | November 26, 2026 |
| Registry record updated | September 24, 2026 |
| Trial ID | NCT07642752 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are males aged 18–45, 12 weeks to 1 year post-ACL reconstruction with hamstring autograft and limited knee flexion (<120°) or mild extension lag.
✕Probably not a fit
Participants outside the criteria (e.g., different grafts, other knee injuries, comorbidities) may receive no added benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares two rehabilitation approaches after ACL reconstruction: perturbation training, which uses unexpected movements to improve stability, and task-oriented functional activities, which mimic daily or sports tasks. Participants 18–45 years old, 12 weeks to 1 year post-surgery, are randomly assigned to one of three groups: perturbation, functional activities, or standard rehab. Outcomes include pain, range of motion, knee stability, and knee function measured by standard scales. The study will be conducted at a physiotherapy clinic and a hospital in Lahore, Pakistan, enrolling 54 participants using convenience sampling.
Why it matters
Potential benefit: If successful, the findings could guide rehab choices to improve knee stability and function after ACL reconstruction.
How similar studies have gone: Previous research supports neuromuscular and functional training approaches for ACL rehab, but direct comparison in this specific post-operative window is less established.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age range: 18-45 years * Male participants only * History of Anterior Cruciate Ligament Reconstruction (ACLR) of 3 to 12 months * No prior ACL surgery on the affected knee * ACL reconstruction with autograft of hamstrings tendon * Knee flexion range of motion less than 120° * Extension lag less than or equal to 10° * Pain during functional activities Exclusion Criteria: * Any type of fracture * Concurrent ligamentous injury or repairable meniscus * Osteochondral defect * Any systemic and/or neurological illness * Rheumatoid arthritis * Osteomyelitis or any neurological disorders * Spinal disorders * Inflammatory conditions such as ankylosing spondylitis
Where it's running
-
Ghurki Hospital Lahore
Lahore, Punjab Province, Pakistan Recruiting
Study contacts
- Principal investigator: Hira Shaukat, Mphill — Riphah International University
- Study coordinator: Imran Amjad, PhD
- Email: Imran.amjad@riphah.edu.pk
- Phone: 03324390125
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.