Longitudinal analysis of Keratoconus patients at the Homburg Keratoconus Center
Official title: The Homburg Keratoconus Center (HKC) - a Keratoconus Observation Study
Run by Universität des Saarlandes · NCT03923101 · Data updated 2026-11-12
This study looks at over 3,000 people with Keratoconus to see how the disease develops over time and to find ways to improve diagnosis and treatment.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 5000 (estimated) |
| Sponsor | Universität des Saarlandes Academic / other |
| Locations | 1 site (Homburg, Saarland) |
| Status | Recruiting |
| Started | January 1, 2011 |
| Main results expected | January 1, 2036 |
| Study ends | January 1, 2036 |
| Registry record updated | April 27, 2026 |
| Trial ID | NCT03923101 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals diagnosed with Keratoconus who are receiving care at the Department of Ophthalmology, Saarland University Medical Center.
✕Probably not a fit
Patients without a diagnosis of Keratoconus will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to conduct both longitudinal and cross-sectional analyses of Keratoconus, a corneal ectatic disease, using data collected from over 3,000 patients at the Homburg Keratoconus Center. The study focuses on analyzing topographic, tomographic, and biomechanical characteristics of the disease to better understand its onset and progression throughout a patient's life. By gathering comprehensive data, the research seeks to provide insights that could improve diagnosis and treatment strategies for Keratoconus.
Why it matters
Potential benefit: If successful, this study could enhance understanding of Keratoconus, leading to improved management and treatment options for patients.
How similar studies have gone: While there have been studies on Keratoconus, this specific longitudinal and comprehensive approach to analyzing the disease's characteristics is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * All Keratoconus patients presenting in the department of ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany. Exclusion Criteria: * Patients without Keratoconus.
Where it's running
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Department of Ophthalmology
Homburg, Saarland, Germany Recruiting
Similar studies
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This trial will test whether twice-daily GLK-221 eye drops are safe and help adults aged 18–55 with keratoconus compared with a placebo.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.