Longitudinal analysis of Keratoconus patients at the Homburg Keratoconus Center

The Homburg Keratoconus Center (HKC) - a Keratoconus Observation Study

Observational Universität des Saarlandes · NCT03923101

This study looks at over 3,000 people with Keratoconus to see how the disease develops over time and to find ways to improve diagnosis and treatment.

Quick facts

Study typeObservational
Enrollment5000 (estimated)
SexAll
SponsorUniversität des Saarlandes Academic / other
Locations1 site (Homburg, Saarland)
Trial IDNCT03923101 on ClinicalTrials.gov

What this trial studies

This observational study aims to conduct both longitudinal and cross-sectional analyses of Keratoconus, a corneal ectatic disease, using data collected from over 3,000 patients at the Homburg Keratoconus Center. The study focuses on analyzing topographic, tomographic, and biomechanical characteristics of the disease to better understand its onset and progression throughout a patient's life. By gathering comprehensive data, the research seeks to provide insights that could improve diagnosis and treatment strategies for Keratoconus.

Who should consider this trial

Good fit: Ideal candidates for this study are individuals diagnosed with Keratoconus who are receiving care at the Department of Ophthalmology, Saarland University Medical Center.

Not a fit: Patients without a diagnosis of Keratoconus will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of Keratoconus, leading to improved management and treatment options for patients.

How similar studies have performed: While there have been studies on Keratoconus, this specific longitudinal and comprehensive approach to analyzing the disease's characteristics is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* All Keratoconus patients presenting in the department of ophthalmology, Saarland University Medical Center, Homburg, Saarland, Germany.

Exclusion Criteria:

* Patients without Keratoconus.

Where this trial is running

Homburg, Saarland

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions KeratoconusCrosslinkingIntracorneal ring segmentsGas-permeable rigid contact-lensesPenetrating KeratoplastyDeep anterior lamellar KeratoplastyABCD Grading System
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.