Link between alcohol use and surgical outcomes at University Hospitals
Role of Phosphatidylethanol in Predicting Perioperative Outcomes of Admitted Patients at UHCMC
University Hospitals Cleveland Medical Center · NCT06864819
This study is trying to see if higher alcohol use, measured by a specific marker in the blood, affects recovery and complications in patients who have elective surgery and stay in the hospital for a few days.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 170 (estimated) |
| Ages | 21 Years to 79 Years |
| Sex | All |
| Sponsor | University Hospitals Cleveland Medical Center (other) |
| Locations | 1 site (Cleveland, Ohio) |
| Trial ID | NCT06864819 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between phosphatidylethanol (PEth) levels, which indicate alcohol consumption, and postoperative complications in patients undergoing elective surgery at University Hospitals Cleveland Medical Center. It focuses on patients who are expected to stay in the hospital for three or more days after surgery, assessing how PEth levels correlate with various complications such as confusion, lung or heart issues, infections, and extended ICU stays. By analyzing these connections, the study aims to provide insights into how alcohol use may impact surgical recovery and outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 21-79 undergoing elective surgery at UHCMC with a planned ICU admission and expected hospital stay of three or more days.
Not a fit: Patients undergoing same-day outpatient surgeries or those expected to be admitted for less than three days post-operatively may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could help identify patients at higher risk for complications based on their alcohol consumption, leading to improved preoperative assessments and tailored care.
How similar studies have performed: While there is limited information on the specific link between PEth levels and surgical outcomes, studies have shown varying impacts of alcohol consumption on health, indicating a need for further exploration in this area.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1\. Age range: 21-79 * 2\. Patients undergoing elective surgery at UHCMC with planned ICU admission * 3\. Patients undergoing elective surgery at UHCMC with expected in-hospital admission for three or more days * 4\. Only patients who consume alcoholic beverages on a regular basis. Exclusion Criteria: * 1\. Patients undergoing same day outpatient surgeries or expected to be admitted less than three days post-operatively * 2\. Subjects who have received a blood transfusion within the past month before surgery * 3\. Pregnant subjects
Where this trial is running
Cleveland, Ohio
- University Hospital — Cleveland, Ohio, United States (RECRUITING)
Study contacts
- Principal investigator: Salim Hayek, MD, PhD — University Hospitals
- Study coordinator: Ayse Ulucay, MD
- Email: ayse.ulucay@uhhospitals.org
- Phone: 216-844-3771
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Postoperative Complications, Alcohol Use Disorder, alcohol consumption, surgical outcomes