Knee Strength After Suprapatellar vs. Infrapatellar Tibial Nailing for Tibia Fractures
Official title: Comparison of the Effects of Suprapatellar and Infrapatellar Tibial Intramedullary Nailing on the Knee Extensor Mechanism in Tibial Shaft Fractures
Run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · NCT07862907 · Data updated 2026-11-12
This study compares knee extensor strength recovery after tibial nailing done through the suprapatellar route versus the infrapatellar route in adults with tibial shaft fractures.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 60 (estimated) |
| Sponsor | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization Academic / other |
| Locations | 1 site (Istanbul, Şişli) |
| Status | Recruiting |
| Started | February 10, 2026 |
| Main results expected | August 2027 |
| Study ends | August 1, 2027 |
| Registry record updated | October 7, 2026 |
| Trial ID | NCT07862907 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults 18–65 with acute AO type 42 tibial shaft fractures treated with intramedullary nailing via suprapatellar or infrapatellar entry at the study center.
✕Probably not a fit
Patients with prior knee surgery, knee ligament injury, intra-articular fracture, bilateral fractures, neurovascular injury, or other injuries that could affect knee strength may not benefit from this comparison.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a prospective, single-center observational cohort study at a major Istanbul hospital. Adults aged 18–65 with acute tibial shaft fractures treated with intramedullary nailing are followed to compare knee extensor muscle strength and function between the suprapatellar and infrapatellar surgical approaches. The treating surgeon determines the approach as part of standard care, and participants are observed without randomization. Follow-up assessments occur at 3 and 6 months postoperatively, focusing on objective knee extensor strength alongside routine clinical recovery metrics. The same rehabilitation principles guide both cohorts, with data collected to understand potential differences attributable to the entry point of the nail.
Why it matters
Potential benefit: If differences are found, surgeons could optimize approach choice to improve knee muscle recovery after tibial nailing.
How similar studies have gone: Previous research has compared pain and patient-reported outcomes between approaches, but objective knee extensor strength data remain limited, making this observational work relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Age between 18 and 65 years Acute tibial shaft fracture classified as AO type 42 Treatment with intramedullary nailing using a suprapatellar or infrapatellar approach Provision of written informed consent to participate in the study Exclusion Criteria: Previous knee surgery. Concomitant knee ligament injury. Intra-articular fracture. Bilateral fractures. Neurovascular injury. Multiple trauma that may affect knee extensor strength, including an ipsilateral femoral fracture or pelvic fracture.
Where it's running
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T.C. İstanbul Prof. Dr. Cemil Taşcıoğlu City Hospital
Istanbul, Şişli, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Müjdat Adaş — Prof.Dr. Cemil Taşçıoğlu City Hospital
- Study coordinator: Furkan Barış, MD
- Email: furkanbariss@gmail.com
- Phone: +905347161615
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.