Preoperative 3D fracture analysis for planning tibial fixation
Official title: Assessment of the Feasibility of Using a Preoperative Surgical Fracture Analysis Tool
Run by Brigham and Women's Hospital · NCT07193524 · Data updated 2026-11-12
This project will try a 3D CT-based tool that helps surgeons plan screw and plate fixation for adults with complex tibial plateau fractures to see if it fits into usual care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Brigham and Women's Hospital Academic / other |
| Locations | 2 sites (Boston, Massachusetts and 1 other locations) |
| Status | Recruiting |
| Started | September 10, 2025 |
| Main results expected | September 2027 |
| Study ends | September 2028 |
| Registry record updated | September 26, 2025 |
| Trial ID | NCT07193524 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with lower extremity fractures, particularly complex tibial plateau fractures, who have preoperative CT imaging and receive care at the participating hospitals are the ideal candidates.
✕Probably not a fit
Patients under 18, those without preoperative CT scans, or those with simple fractures that do not require complex fixation are unlikely to benefit from this tool.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
The tool creates patient-specific 3D visualizations from CT scans and uses biomechanical modeling to simulate different screw and plate fixation strategies for tibial fractures. Surgeons review simulated constructs and stability metrics preoperatively to inform their planned fixation approach. The study tests whether this workflow can be integrated into usual preoperative planning at two Boston academic centers without changing the standard of care. Feasibility outcomes focus on workflow fit, surgeon usability, and whether the tool changes preoperative plans.
Why it matters
Potential benefit: If successful, the tool could help surgeons choose more stable fixation plans, potentially reducing intraoperative uncertainty, operative time, and fixation-related complications.
How similar studies have gone: Prior work using 3D modeling and biomechanical simulation in orthopedic planning has shown promising technical results, though clear clinical outcome improvements and broad adoption are still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age above 18 * lower extremity fracture
Where it's running
-
Massachusetts General Hospital
Boston, Massachusetts, United States Recruiting -
Brigham and Women's Hospital
Boston, Massachusetts, United States Recruiting
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Trauma registry at Sohag University Hospital
This study tests the creation of a trauma registry in the emergency department to collect data on injured adults admitted with polytrauma at Sohag University Hospital.
-
Knee Strength After Suprapatellar vs. Infrapatellar Tibial Nailing for Tibia Fractures
This study compares knee extensor strength recovery after tibial nailing done through the suprapatellar route versus the infrapatellar route in adults with tibial shaft fractures.
-
Kidney and liver blood flow patterns after major trauma
We will use bedside ultrasound to see whether abnormal kidney and liver blood flow patterns occur in adults admitted to the ICU after major trauma and whether those patterns link to acute kidney injury or the need for mechanical ventilation.
-
Mortality in the ICU after trauma in Colombia
This study tests what factors are linked to death among trauma patients admitted to the ICU and compares them with other ICU admissions in Colombian hospitals.
-
Sweet almonds to help heal femur and tibia shaft fractures
This test will see if eating sweet almonds helps adults aged 18–55 with trauma-related femur or tibia shaft fractures heal their bones faster and safely.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.