Clinical trial Recruiting at 1 site Observational Ages 18 to 90

Does warming patients before surgery affect lactate levels after nephrectomy?

Official title: Effect of Preoperative Active Prewarming on Serum Lactate Levels and Perioperative Outcomes in Patients Undergoing Elective Nephrectomy: A Prospective Observational Study

Run by Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization · NCT07702487 · Data updated 2026-11-12

This observational study looks at whether warming patients before kidney removal surgery changes blood lactate and helps recovery.

Quick facts

Study typeObservational
Ages18 Years to 90 Years
SexAll
Enrollment128 (estimated)
SponsorProf. Dr. Cemil Tascıoglu Education and Research Hospital Organization
Academic / other
Locations1 site (Istanbul, Sisli)
StatusRecruiting
StartedNovember 15, 2025
Main results expectedNovember 15, 2026
Study endsNovember 15, 2026
Registry record updatedJuly 14, 2026
Trial IDNCT07702487 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18–90 undergoing elective nephrectomy with ASA I–III, able to provide informed consent, and with complete pre/postoperative measurements.

Probably not a fit

Findings may show no difference between prewarming and no prewarming groups or no impact on the specific outcomes studied.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, single-center observational study of adults undergoing elective nephrectomy. Researchers compare patients who receive preoperative warming to those who do not, as decided by the anesthesia team in routine care. The goal is to see if prewarming influences perioperative lactate levels and outcomes such as ICU stay, transfusion needs, and complications. Data are collected from pre- and postoperative periods without altering standard clinical practice. The study duration covers one year and includes adults aged 18 to 90 with ASA I–III status.

Why it matters

Potential benefit: If prewarming is associated with lower lactate or better recovery, it could support simple, low-risk changes to perioperative care.

How similar studies have gone: Previous work in perioperative warming has suggested metabolic benefits in some settings, but data specific to nephrectomy and lactate are limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Scheduled for elective nephrectomy
* Adults aged 18-90 years
* ASA (American Society of Anesthesiologists) physical status classification I-III
* Signed informed consent form

Exclusion Criteria:

* Emergency nephrectomy
* Concurrent additional major surgical procedure planned in the same session
* Age under 18 or over 90 years
* ASA physical status classification IV or higher
* Incomplete preoperative records (missing pre- or postoperative measurement of at least one primary outcome variable)

Where it's running

  • Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization
    Istanbul, Sisli, Turkey (Türkiye)
    Recruiting

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.