Knee injury and degeneration in real-world care
Official title: Bidirectional Cohort of Lower-Extremity Sports Injuries and Degeneration (Yongjiang Cohort)
Run by Ningbo No.2 Hospital · NCT07592871 · Data updated 2026-11-12
This study follows patients with knee injuries or osteoarthritis to see how they recover over 2 years when they get standard care.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 90 Years |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Ningbo No.2 Hospital Academic / other |
| Locations | 1 site (Ningbo, Zhejiang) |
| Status | Recruiting |
| Started | June 1, 2026 |
| Main results expected | May 31, 2028 |
| Study ends | May 31, 2028 |
| Registry record updated | August 17, 2026 |
| Trial ID | NCT07592871 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults with knee-related injuries or degenerative knee disease who are receiving routine clinical care at Ningbo No. 2 Hospital and can complete baseline and follow-up assessments.
✕Probably not a fit
Patients unlikely to benefit are those unable to complete baseline or follow-up assessments or with conditions preventing participation in follow-up.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational cohort study conducted at Ningbo No. 2 Hospital to build a real-world cohort of patients with knee sports injuries or degenerative knee disease. Baseline data include medical history, labs, questionnaires, X-ray, MRI, and functional tests; younger participants focus on sports-related outcomes while older participants undergo additional sarcopenia assessments. Participants are followed roughly at 6, 12, and 24 months after their treatment or surgery to monitor knee function, imaging changes, and reinjury, with no experimental interventions involved. Data sources include baseline and historical information along with prospective follow-up.
Why it matters
Potential benefit: Participants may benefit from closer monitoring of knee health and more informed long-term care decisions through comprehensive follow-up data.
How similar studies have gone: Similar observational cohorts have provided valuable real-world insights into knee injury and degeneration trajectories, though this specific design is focused on a single center.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients who plan to receive relevant clinical evaluation or treatment at Ningbo No. 2 Hospital and are able to complete baseline assessment. * Patients with a clinical diagnosis of knee-related injury or degenerative knee disease. * Patients who are willing to provide informed consent and participate in follow-up. Exclusion Criteria: * Patients who are unable to complete the core baseline assessments or have substantial missing key clinical information. * Patients with severe comorbid conditions or cognitive impairment that may affect assessment of the main outcomes or prevent participation in follow-up. * Patients who are considered by the investigator to be unsuitable for inclusion in this cohort.
Where it's running
-
Ningbo NO.2 Hospital,Wenzhou Medical University
Ningbo, Zhejiang, China Recruiting
Study contacts
- Study coordinator: Yi Yuan, MD
- Email: yct1124@alumni.sjtu.edu.cn
- Phone: +86 18858234093
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.