Investigation of VAP-1 Expression and Tissue Blood Flow by PET-MRI in Patients With Crohn's Disease

Investigation of VAP-1 Expression and Tissue Blood Flow by Combined [68Ga]DOTA-Siglec-9 and [15O]H2O PET-MRI in Patients With Small Bowel's Crohn's Disease

Observational Turku University Hospital · NCT06555042

This study is testing if a special imaging technique can help us understand blood flow and a specific protein in the tissues of people with Crohn's disease.

Quick facts

Study typeObservational
Enrollment20 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorTurku University Hospital Government
Locations1 site (Turku, Southwest Finland)
Trial IDNCT06555042 on ClinicalTrials.gov

What this trial studies

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Who should consider this trial

Good fit: Unknown

Not a fit: Unknown

Why it matters

Potential benefit: Unknown

How similar studies have performed: Unknown

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults between age 18-70
* Strong clinical suspicion of small bowel Crohn's disease
* Able and willing to give written informed consent and to comply with the study protocol

Exclusion Criteria:

* Pregnant or breast-feeding women
* Previous capsule retention
* X-ray investigations during preceding year
* Patients with metallic implants such as an electronic pacemaker or an implanted infusion pump
* Known stenosis of the GI-tract
* Evidence of significant uncontrolled concomitant diseases such as neurological, renal, hepatic, endocrine, or gastrointestinal disorders which, in the opinion of the Investigator, would preclude patient participation
* Is unable or unwilling to comply with the study protocol for any reason

Where this trial is running

Turku, Southwest Finland

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Crohn DiseaseInflammatory Bowel DiseasesCrohn Disease of Small IntestineCrohn ColitisCrohn's IleocolitisCrohn Disease in RemissionInflammatory Bowel DiseasePositron emission tomography
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.