Clinical trial No longer in our active list Observational Ages 18 and up

Investigating the role of a lipid transporter in colorectal cancer inflammation

Official title: The Role of Lipid Transporter MFSD2A in the Resolution of Colorectal Cancer-associated Inflammation: Implications for New Therapeutic Strategies

Run by IRCCS San Raffaele · NCT06071598 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is trying to understand how a specific lipid transporter affects inflammation in colorectal cancer to see if it can lead to new treatments for patients with this condition.

More Colorectal Cancer trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment15 (estimated)
SponsorIRCCS San Raffaele
Academic / other
Locations1 site (Milan)
Trial IDNCT06071598 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with colorectal cancer, particularly those with varying tumor stages.

Probably not a fit

Patients who have undergone previous intestinal resection or are taking specific medications like trace elements or hypolipemiants in the last three months may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the role of the lipid transporter MFSD2A in the resolution of inflammation associated with colorectal cancer (CRC). It focuses on understanding how inflammation contributes to tumor promotion in CRC patients, particularly those with inflammatory bowel diseases. The study involves analyzing surgical specimens from CRC-affected patients, stratified by tumor stage, to uncover potential mechanisms that could lead to new therapeutic approaches targeting cancer-associated inflammation.

Why it matters

Potential benefit: If successful, this study could lead to the development of novel therapies that effectively manage inflammation in colorectal cancer without compromising the body's natural defenses.

How similar studies have gone: While the connection between inflammation and cancer is well-established, this specific approach focusing on MFSD2A is novel and has not been extensively tested in previous studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

- 15 CRC-affected patients stratified according to tumor stage (T0/T1-T4, M0/M1, N0/N1/N2)

Exclusion Criteria:

Patients:

* taking trace elements, hypolipemiants in the previous 3 months
* undergone previous intestinal resection

Where it's running

  • IRCCS Ospedale San Raffaele
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.