Investigating oxygen levels during bronchoscopy procedures
To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation
This study is trying to see how much oxygen is in the airways during bronchoscopy procedures for patients with blocked airways to understand the risks of airway fires.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Minnesota Academic / other |
| Locations | 1 site (Minneapolis, Minnesota) |
| Trial ID | NCT05881863 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate airway oxygen concentrations during rigid bronchoscopy procedures performed with high frequency jet ventilation. It focuses on patients with central airway obstruction who require thermal ablation treatments. The study will collect data on the concentration of oxygen in the airways during these procedures to better understand the risks associated with airway fire. The research is being conducted at the University of Minnesota, where patients undergoing the procedure will be monitored for oxygen levels.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older undergoing rigid bronchoscopy for central airway obstruction.
Not a fit: Patients who are pregnant, have hemodynamic or respiratory instability, or are ineligible for rigid bronchoscopic intubation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the safety of bronchoscopy procedures by providing critical data to minimize the risk of airway fires.
How similar studies have performed: There is currently no published literature on airway oxygen concentrations during jet ventilation with rigid bronchoscopy, making this a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients undergoing rigid bronchoscopy for treatment of central airway obstruction at FV UMMC will be identified. * 18 years or older * Need rigid bronchoscopy as pre-determined by the interventional pulmonologist Exclusion Criteria: * Refusal to sign consent * Pregnant patients * Hemodynamic instability defined as continuous infusion of medication in order to support blood pressure and/or heart rate/rhythm * Respiratory instability defined as SpO2\<90% with \>90% supplemental oxygen. * Ineligible for rigid bronchoscopic intubation * Latex allergy * Evidence of fistulous airway * Active Bronchopleural fistula
Where this trial is running
Minneapolis, Minnesota
- University of Minnesota — Minneapolis, Minnesota, United States (Recruiting)
Study contacts
- Principal investigator: Sudarshan Setty, MD — University of Minnesota
- Study coordinator: Candace Nelson
- Email: nelso377@umn.edu
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.