Investigating organ dysfunction in COVID-19 patients in intensive care
Uppsala Intensive Care Study of Mechanisms for Organ Dysfunction in Covid-19
This study is trying to see how COVID-19 affects organ function in patients in intensive care by looking at their blood, urine, and sputum samples.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Uppsala University Academic / other |
| Locations | 1 site (Uppsala) |
| Trial ID | NCT04316884 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients with suspected or confirmed COVID-19 who are admitted to the intensive care unit at Uppsala University Hospital. Participants will provide daily blood, urine, and sputum samples during their stay, which will be analyzed for biomarkers associated with organ dysfunction. Data regarding organ dysfunction will be collected through electronic patient records and management systems to correlate these biomarkers with clinical outcomes. The goal is to enhance understanding of the mechanisms behind organ dysfunction in COVID-19 patients.
Who should consider this trial
Good fit: Ideal candidates for this study are adults admitted to intensive care with suspected or verified COVID-19.
Not a fit: Patients who are pregnant, breastfeeding, or underage will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved diagnosis and treatment strategies for organ dysfunction in COVID-19 patients.
How similar studies have performed: Other studies have explored organ dysfunction in COVID-19, but this specific approach focusing on biomarker correlation is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Admitted to intensive care * suspected or verified COVID-19 Exclusion Criteria: * Pregnancy or breastfeeding * Under-age
Where this trial is running
Uppsala
- Uppsala University Hospital — Uppsala, Sweden (Recruiting)
Study contacts
- Principal investigator: Robert Frithiof, MD. PhD — Uppsala University Hospital
- Study coordinator: Robert Frithiof, MD. PhD.
- Email: robert.frithiof@surgsci.uu.se
- Phone: 0736563473
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.