Investigating insulin resistance in non-diabetic patients with acute coronary syndrome

Effects of Insulin Resistance in Non-diabetic Acute Coronary Syndrome Patients by the Homeostasis Model Assessment Index (HOMA2-IR)

Not applicable Interventional University of Medicine and Pharmacy at Ho Chi Minh City · NCT06163768

This study is testing how insulin resistance affects people without diabetes who are having a heart problem to see if it can help prevent future health issues.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment1 (estimated)
Ages18 Years to 60 Years
SexAll
SponsorUniversity of Medicine and Pharmacy at Ho Chi Minh City Academic / other
Locations1 site (Ho Chi Minh City, Five)
Trial IDNCT06163768 on ClinicalTrials.gov

What this trial studies

This study examines the effects of insulin resistance in patients experiencing acute coronary syndrome who do not have diabetes. By utilizing the homeostasis model assessment index (HOMA2-IR), the research aims to enhance understanding of insulin resistance and its long-term implications, such as the risk of developing type 2 diabetes. The goal is to provide healthcare professionals with insights that could lead to more effective monitoring and treatment strategies, ultimately preventing diabetes and cardiovascular events.

Who should consider this trial

Good fit: Ideal candidates include adults over 18 years old diagnosed with acute coronary syndrome who do not have diabetes.

Not a fit: Patients with a history of diabetes or those under 18 years old may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved monitoring and treatment strategies for patients at risk of diabetes and cardiovascular issues.

How similar studies have performed: While the specific approach may be novel, studies on insulin resistance and its implications in cardiovascular health have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Control group The researcher collected samples from healthy people over 18 years old who came for a health check and were concluded to have good health at the Health Examination Department of University of Medicine and Pharmacy Hospital, Ho Chi Minh City. Not falling within the exclusion criteria and agreeing to participate in the study were included in the study.
* Researchers -All patients diagnosed with Acute coronary syndrome who were over 18 years old, met the inclusion criteria and did not have exclusion criteria, and agreed to participate in the study were included in the study.

Exclusion Criteria:

* Control group

  * Patients \< 18 years old.
  * History of heart disease or stroke
  * Exclude diabetic subjects
  * Exclude subjects at high risk of insulin resistance
* Researchers

  * Have diabetes or have previously been diagnosed with diabetes.
  * Patients \< 18 years old.
  * The patient does not participate in follow-up examinations and does not follow up treatment at the medical facility.
  * The patient died before reaching the hospital.
  * Patients with severe medical diseases: cirrhosis, cancer, obstructive pulmonary disease chronic obstructive pulmonary disease, chronic heart failure, severe kidney failure.

Where this trial is running

Ho Chi Minh City, Five

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Insulin Resistance
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.