Investigating how lung diseases affect heart function
Official title: The Relationship Between Pulmonary and Cardiac Dysfunction and the Cardiac Effects of Pulmonary Treatments: Cardiopulmonary MRI Analysis
Run by RWTH Aachen University · NCT05042219 · Data updated 2026-11-12
This study is trying to see how chronic lung diseases like COPD and asthma affect heart function in patients using special heart imaging techniques.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 99 Years |
| Sex | All |
| Enrollment | 120 (estimated) |
| Sponsor | RWTH Aachen University Academic / other |
| Locations | 1 site (Aachen) |
| Status | Recruiting |
| Started | June 1, 2022 |
| Main results expected | September 14, 2026 |
| Study ends | December 14, 2026 |
| Registry record updated | July 16, 2024 |
| Trial ID | NCT05042219 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults over 18 years with chronic lung diseases such as COPD, asthma, or pulmonary fibrosis who require treatment.
✕Probably not a fit
Patients who are unable to provide informed consent, have contraindications to MRI, or significant cardiac arrhythmias may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the interactions between chronic lung diseases, such as COPD, bronchial asthma, and idiopathic pulmonary fibrosis, and their impact on cardiac function, particularly the left heart. It utilizes cardiac magnetic resonance imaging (MRI) to assess cardiac function and dimensions, as well as myocardial inflammation in affected patients. The study seeks to fill the knowledge gap regarding the cardiopulmonary interactions that are not well understood, despite the known bidirectional relationship between the lungs and the right heart. By examining these interactions, the study hopes to provide valuable insights for clinicians treating patients with chronic lung conditions.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how lung diseases influence heart function, leading to improved treatment strategies for patients with chronic lung conditions.
How similar studies have gone: While the interactions between lung diseases and the right heart are well-studied, this investigation into the left heart's involvement is relatively novel and has not been extensively researched.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with chronic lung disease requiring treatment (COPD, asthma, or pulmonary fibrosis). * Age \> 18 years * Informed consent to participate in the study will sign Exclusion Criteria: * Individuals who are not fully capable of giving consent and understanding the nature, significance and scope of the study. * Patients with contraindications to MRI examination (eg, pacemaker, severe claustrophobia) or to contrast medium use (severe renal insufficiency or glomerular filtration rate \<30 ml/min, known gadolinium contrast medium allergy) * Patients with atrial fibrillation or other significant cardiac arrhythmias that interfere with cardiac MRI * Pregnancy and lactation
Where it's running
-
University Hospital RWTH Aachen
Aachen, Germany Recruiting
Study contacts
- Study coordinator: Ayham Daher, M.D.
- Email: adaher@ukaachen.de
- Phone: +492418088763
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.