Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Community- or home-based exercise for adults with weakened heart or lungs

Official title: Clinical Study Protocol on the Impact of Community-Based Exercise Training on the Exercise Capacity of Patients With Reduced Cardiovascular and Pulmonary Function

Run by Guangdong Provincial People's Hospital · NCT07154355 · Data updated 2026-11-12

This test will see if an eight-week, community- or home-based exercise program can improve heart and lung function in adults 18–85 with reduced cardiopulmonary fitness.

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment200 (estimated)
SponsorGuangdong Provincial People's Hospital
Academic / other
Locations1 site (Guangzhou, Guangdong)
StatusRecruiting
StartedJanuary 30, 2025
Main results expectedDecember 2029
Study endsDecember 2030
Registry record updatedSeptember 4, 2025
Trial IDNCT07154355 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18–85 with documented reduced pulmonary or cardiovascular function who pass a medical screening and have not done regular structured moderate-to-intense training in the past year are the intended participants.

Probably not a fit

Patients with neuromuscular or skeletal disorders, systemic diseases such as diabetes or cancer, those taking medications that interfere with outcomes, or people already engaged in organized moderate-to-high intensity training are unlikely to benefit from this program.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Participants will be assigned to a community- or home-based exercise program or to a non-exercise comparator to compare changes in cardiovascular and pulmonary function. The exercise intervention lasts eight weeks and consists of 40–60 minutes per session, five times weekly, with activities chosen from walking, running, swimming, cycling, hiking, or similar patient-preferred modalities. Exercise intensity is adjusted using each participant's cardiopulmonary exercise test and ongoing monitoring to emphasize safety and adherence. The study aims to establish a feasible community/home fitness program that improves function while reducing the burden of clinic-based rehabilitation.

Why it matters

Potential benefit: If successful, this approach could improve cardiopulmonary function, daily exercise tolerance, and make rehabilitation more accessible with less reliance on clinic-based programs.

How similar studies have gone: Previous cardiac and pulmonary rehabilitation studies, including some home- and community-based programs, have shown improvements in function and adherence, so this approach has supporting evidence.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Patients aged 18 to 85 with abnormal pulmonary or cardiovascular function.
2. Individuals who have completed a medical screening form to confirm they are free from illnesses and prescription medications that could impair their ability to complete the required testing and fitness training.
3. Participants who did not engage in structured, systematic moderate-to-intense strength or endurance training during the study period (specifically, not within the previous year).
4. At the onset of the trial, participants were physically active but had never participated in formal exercise more than twice a week.

Exclusion Criteria:

1. Patients with neuromuscular or skeletal disorders, or systemic diseases such as diabetes, cancer, or heart disease.
2. Individuals using medications known to affect health or the interpretation of study results.
3. Participants who have engaged in organized, systematic endurance or strength training of moderate to high intensity within the past year.
4. Patients who decline to participate in the study.
5. Other medical conditions or states that render exercise training inappropriate.

Where it's running

  • Department of Rehabilitation Medicine Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences)
    Guangzhou, Guangdong, China
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.