Investigating how diet affects heart health and gut bacteria in Singapore adults
Associations Between Dietary Intake and Cardiometabolic and Gut Microbiota Outcomes in Singapore Adults
This study looks at how different diets affect heart health and gut bacteria in adults in Singapore to see what eating habits might be better for their overall health.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 240 (estimated) |
| Ages | 21 Years to 80 Years |
| Sex | All |
| Sponsor | National University of Singapore Academic / other |
| Locations | 1 site (Singapore, Singapore) |
| Trial ID | NCT06775132 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationships between dietary intake, cardiometabolic health markers, and gut microbiota composition among adults in Singapore. It recognizes the significant role diet plays in chronic disease development and seeks to fill the gap in research focused on Asian populations, which have been underrepresented in previous studies. By assessing these associations, the study aims to identify specific dietary patterns or nutrients that may benefit cardiometabolic and gut health. The findings could lead to improved dietary guidelines tailored for this population.
Who should consider this trial
Good fit: Ideal candidates for this study are English-literate adults aged 21-80 years who have not made drastic dietary changes in the past year.
Not a fit: Patients taking dietary supplements or medications that affect gut microbiota or sleep outcomes may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights that lead to better dietary recommendations for improving cardiometabolic health and gut microbiota in Singaporean adults.
How similar studies have performed: While many studies have explored diet and health in Western populations, this study's focus on an Asian population is relatively novel and untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Able to give informed consent 2. Adults 21-80 years old 3. English-literate 4. Have venous access sufficient to allow for blood sampling as per the protocol 5. No drastic change of diet for the past 1 year 6. If taking medication, has been consistently taking antihypertensive/cholesterol-lowering/type-2 diabetic medication for more than 5 years prior to starting the study. Exclusion Criteria: 1. Taking dietary supplements and fermented foods, which may impact the gut microbiota (e.g. antibiotics, prebiotics, probiotics, yogurt, kimchi) 2 months before starting the 1st study visit only. 2. Taking dietary supplements or medications, which may impact sleep outcomes (e.g. Nutritional Shakes (e.g. Ensure), tryptophan, 5-hydroxytryptophan or melatonin supplementations) 1 month before starting the study. 3. Taking dietary supplements which may impact the eye outcomes (e.g. Vitamin A, vitamin A-containing multivitamin) 2 months before starting the study.
Where this trial is running
Singapore, Singapore
- National University of Singapore — Singapore, Singapore, Singapore (Recruiting)
Study contacts
- Principal investigator: Jung Eun Kim — Department of Food Science and Technology, National University of Singapore
- Study coordinator: Yao Yueying
- Email: yueying.yao@u.nus.edu
- Phone: +65 83136733
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.