Investigating heart failure in middle-aged women with adverse pregnancy outcomes
Middle-aged Women With Adverse Pregnancy Outcomes and Heart Failure With Preserved Ejection Fraction
National Medical Research Center for Therapy and Preventive Medicine · NCT06338943
This study is looking at whether middle-aged women who had problems during pregnancy are more likely to develop heart failure with preserved ejection fraction (HFpEF).
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 45 Years to 60 Years |
| Sex | Female |
| Sponsor | National Medical Research Center for Therapy and Preventive Medicine (other gov) |
| Locations | 1 site (Moscow) |
| Trial ID | NCT06338943 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between heart failure with preserved ejection fraction (HFpEF) and adverse pregnancy outcomes in middle-aged women. It will assess the frequency of adverse pregnancy outcomes in women with and without HFpEF and compare their clinical and historical data. The study utilizes echocardiography and questionnaires to gather relevant information from participants. The goal is to identify potential markers and predictors for HFpEF development linked to pregnancy complications.
Who should consider this trial
Good fit: Ideal candidates are middle-aged women who have experienced adverse pregnancy outcomes and are undergoing echocardiography.
Not a fit: Patients with a left ventricle ejection fraction below 50% or those who refuse to participate will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and early identification of heart failure risks in women with adverse pregnancy histories.
How similar studies have performed: While the relationship between pregnancy complications and heart failure is being explored, this specific focus on HFpEF in middle-aged women is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * All patients who administer to the Federal State Budgetary Institution National Medical Research Center for Therapy and Preventive Medicine, who are undergoing echocardiography for medical reasons * Pregnancy \>20 weeks in the anamnesis * Signed informed consent to participate in the study Exclusion Criteria: * Refusal to sign an informed consent to participate in a clinical trial and to process personal data * Detection of left ventricle ejection fraction \< 50% according to Echocardiography data
Where this trial is running
Moscow
- National Medical Research Center for Therapy and Preventive Medicine — Moscow, Russian Federation (RECRUITING)
Study contacts
- Study coordinator: Max Shperling, MD
- Email: MaxCardio@yandex.ru
- Phone: +79118170034
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Heart Failure Preserved Ejection Fraction, Pregnancy Complications, Adverse Pregnancy Outcomes, Arterial Hypertension, Gestational Diabetes, Mediation