Investigating factors that lead to epilepsy after a stroke
Official title: Predisposing Factors for Post-stroke Epilepsy
Run by Norwegian University of Science and Technology · NCT05864547 · Data updated 2026-11-12
This study is trying to find out what factors might cause epilepsy in people who have had a stroke by comparing them to healthy individuals.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 85 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Norwegian University of Science and Technology Academic / other |
| Locations | 1 site (Trondheim) |
| Status | Recruiting |
| Started | May 8, 2023 |
| Main results expected | December 2030 |
| Study ends | December 2030 |
| Registry record updated | July 7, 2026 |
| Trial ID | NCT05864547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are first-time stroke patients admitted to the stroke unit at St. Olavs Hospital with a modified Rankin Scale score of 2 or less before the stroke.
✕Probably not a fit
Patients with a history of previous strokes, brain surgeries, or pre-existing epilepsy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to understand the risk factors contributing to post-stroke epilepsy by comparing first-time stroke patients with healthy controls. Participants will undergo various assessments including electroencephalography (EEG), magnetic resonance imaging (MRI), and polysomnography to evaluate the relationship between stroke characteristics, inflammation markers, and sleep patterns. The study will also analyze medical records from stroke patients at St. Olavs Hospital to gather comprehensive data on potential predisposing factors. The goal is to identify clinical factors that may influence the development of epilepsy following a stroke.
Why it matters
Potential benefit: If successful, this study could lead to better understanding and management of post-stroke epilepsy, potentially improving patient outcomes.
How similar studies have gone: While studies on post-stroke epilepsy exist, this specific approach focusing on sleep and inflammation markers in a controlled observational setting is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * First time stroke patients with capacity to consent, admitted to the stroke unit at St. Olavs hospital. * Modified Rankin Scale (mRS) ≤ 2 before the stroke Exclusion Criteria: * Previous stroke or brain surgery * Traumatic brain injuries * Neurodegenerative diseases * Brain tumors * Epilepsy before the stroke * Hydrocephalus * Aphasia * Serious psychiatric disorders * MRI incompatibility and claustrophobia
Where it's running
-
St. Olavs Hospital Stroke Unit
Trondheim, Norway Recruiting
Study contacts
- Principal investigator: Axel Sandvig, PhD prof — Norwegian Science and Technology University
- Study coordinator: Axel Sandvig, PhD prof
- Email: axel.sandvig@ntnu.no
- Phone: +47 47333042
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.