Investigating factors affecting glioblastoma outcomes

Key Longitudinal Associations With Risk and Glioblastoma Outcomes

Observational Duke University · NCT06625684

This study is looking to see how different health and lifestyle factors affect the survival and quality of life for adults with glioblastoma, a tough type of brain cancer.

Quick facts

Study typeObservational
Enrollment200 (estimated)
Ages18 Years and up
SexAll
SponsorDuke University Academic / other
Locations1 site (Durham, North Carolina)
Trial IDNCT06625684 on ClinicalTrials.gov

What this trial studies

This observational study aims to identify the various factors that influence health outcomes and risks in adults diagnosed with glioblastoma, a highly aggressive brain cancer. Participants will complete an online survey regarding their medical history and lifestyle, and may provide a blood sample for genetic and immune system testing. The study will follow participants over time to observe how these factors impact survival and quality of life. Insights gained may lead to personalized treatment strategies and improved risk assessment tools for glioblastoma management.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older with a pathologically-confirmed diagnosis of glioblastoma multiforme.

Not a fit: Patients who cannot read English or Spanish or those unable to complete an online survey may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance understanding of glioblastoma and lead to improved management strategies for patients.

How similar studies have performed: Other studies have explored factors affecting glioblastoma outcomes, but this specific approach focusing on genetic and immune factors is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* At least 18 years old
* Pathologically-confirmed diagnosis of glioblastoma multiforme (GBM) or grade 4 brain tumor
* Participant is accessible for follow-up (has a working email address)
* Participant is willing and able to comply with the study requirements

Exclusion Criteria:

* Those who cannot read either English or Spanish
* Those who cannot view an online survey

Where this trial is running

Durham, North Carolina

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Glioblastomagenetic predisposition to diseaserisk factorsquality of lifequestionnairesblood sampleadult brain cancerobservational study
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.