Investigating dizziness and muscle weakness in older colorectal cancer patients during chemotherapy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to understand the causes of dizziness and walking difficulties in older adults aged 65 and above undergoing chemotherapy for colorectal cancer. It will assess the effectiveness of a comprehensive geriatric assessment and a specialized physical exercise program conducted three times a week over three months. The study focuses on addressing issues such as sarcopenia, vertigo, and impaired balance, which are often overlooked in this population. By combining geriatric assessments with targeted rehabilitation, the trial seeks to improve the quality of life and treatment outcomes for older cancer patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Meet the criteria of the oncological departments of receiving neoadjuvant, adjuvant or first line palliative chemotherapy for colorectal cancer
* ≥65 years of age at the time of signing the informed consent form
* Able to speak and read Danish, and to provide a signed informed consent form
* Have an Eastern Cooperative Oncology Group (ECOG) performance status score of ≤2

Exclusion Criteria:

* Chemotherapy treatment within two years and sequelae of neuropathy, or symptoms of dizziness or vertigo, or balance disturbance
* Severe physical disability that hinders physical exercise
* Dementia, psychotic disorders, or other cognitive diseases or conditions that hinder participation in a clinical exercise-based trial
* Inability to sign informed content
* Patients who have had a consultation in the geriatric outpatient clinic within the past six months

Where it's running

• Copenhagen University Hospital - Herlev and Gentofte Hospital
  Herlev, Denmark Recruiting
• Copenhagen University Hospital - Rigshospitalet
  Copenhagen, Denmark Not yet recruiting

Study contacts

• Study coordinator: Katrine S Piper, PhD-Student
• Email: katrine.storm.piper@regionh.dk
• Phone: +4551156140

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.