Investigating brain tumors and their evolution

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to analyze the locations and structural aspects of brain tumors in patients of all ages, comparing this data with the evolutionary biology of the brain and skull in vertebrates. It will involve screening approximately 10,000 patients diagnosed with primary brain tumors from 2005 to 2023, utilizing imaging data from CT and MRI scans. The study will manually segment tumor areas and apply machine learning algorithms to automate the segmentation process for a larger dataset, ultimately generating density maps to visualize tumor locations quantitatively by patient age.

Why it matters

Who can join: the full rules

Inclusion Criteria:

• All patients diagnosed with primary brain tumors with available pre/ post-operative or pre-radiation brain images with computed tomography (CT) or magnetic resonance imaging (MRI)

Exclusion Criteria:

* CT/ MRI is not available before cranial radiotherapy
* Artifacts causing distortion of skull (bony) anatomy

Where it's running

• Tata Memorial Hospital
  Mumbai, Maharashtra, India Recruiting

Study contacts

• Principal investigator: Archya Dasgupta, Md — Tata Memorial Hospital
• Study coordinator: Archya Dasgupta, Md
• Email: archya1010@gmail.com
• Phone: 91-22-24177000

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.