Delirium and cognitive changes in older adults in hospital isolation

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, observational cohort study follows patients aged 70 and older who require isolation precautions in the hospital and compares them to matched non-isolated peers. Delirium screening is conducted twice daily using the 3D-CAM, and cognitive function is reassessed six weeks after hospital discharge with the MOCA test, comparing it to baseline. Patients are followed from enrollment during hospitalization (Days 1-5) through six weeks post-discharge to assess delirium incidence, cognitive outcomes, and quality of life. Matching factors include age, gender, Charlson Comorbidity Index, frailty status, and hospital department. The study aims to clarify whether isolation may contribute to higher delirium risk and subsequent cognitive impairment in older adults.

Why it matters

Who can join: the full rules

Inclusion Criteria: - hospitalized patients

* under isolation precautions for at least 24h
* 70 years and above

Exclusion Criteria: - no informed consent

* intensive care treatment
* life expectancy 14 days or less

Where it's running

• Hamburg University Medical Centre Eppendorf
  Hamburg, Free and Hanseatic City of Hamburg, Germany Recruiting

Study contacts

• Principal investigator: Cynthia Olotu, Dr., MD — University Medical Centre Hamburg, Department of Anaesthesiology
• Study coordinator: Cynthia Olotu, Dr., MD
• Email: c.olotu@uke.de
• Phone: 0049 40 7410 52415

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.