Investigating bacteria in gallbladders of patients undergoing surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to explore the presence of bacteria in the gallbladder wall and bile of patients undergoing cholecystectomy. It compares two groups: those with acute calculous cholecystitis and those without, to assess the effectiveness of standard antibiotic treatments against common pathogens. Additionally, the study will examine the correlation between bacterial presence and inflammation severity, potentially predicting infection causes in cholecystitis cases. The findings could enhance the understanding of antibiotic choices for gallbladder infections.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age above 18 years
* Signed consent form
* Patients having cholecystectomy performed at the Department of Surgery, Sygehus Lillebælt, Kolding.

Exclusion Criteria:

* Administration of any type of antibiotics one month prior to surgery in the control group.
* Previous instrumentation of the bileducts
* Previous clinical acute cholecystitis treated conservatively with antibiotics

Patients will be precluded from the studypopulation in cases of pPerioperative perforation of the gallbladder, or conversion to open cholecystectomy or in cases of failed attempts to extract bile or samples from the gallbladder wall.

Where it's running

• Sygehus Lillebælt
  Kolding, Denmark Recruiting

Study contacts

• Principal investigator: Malene B Dissing, MD — Organkirurgisk afdeling, sygehus lillebælt, Kolding
• Study coordinator: Malene B Dissing, MD
• Email: malene.borgager@rsyd.dk
• Phone: 004528745840

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Using chlorination to reduce infections in newborns

  This study is testing if using chlorinated water in hospitals can help reduce infections in mothers and newborns in western Kenya.

  Recruiting University of California, Berkeley · Berkeley, California and 1 other locations · NCT06824350

• Reducing the spread of antibiotic-resistant infections from hospitals to communities

  This study is testing a set of strategies to see if they can help stop the spread of antibiotic-resistant infections from hospitals to families and communities.

  Recruiting Hanoi University of Public Health · Thái Bình, Thai Binh · NCT05871476

• Assessing H. pylori infection rates and antibiotic resistance in Germany

  This study is trying to find out how common H. pylori infections are in Germany and if the bacteria are resistant to antibiotics, so doctors can better treat patients.

  Recruiting Technical University of Munich · Munich · NCT05561504

• Using broad-spectrum antibiotics to prevent infections in orthopedic surgery

  This study tests whether using a stronger type of antibiotics before orthopedic surgery can help prevent infections in patients who are at high risk.

  Recruiting Phase 3 Balgrist University Hospital · Zurich · NCT05502380

• Using pivmecillinam with amoxicillin/clavulanic acid for treating complicated urinary tract infections

  This study is testing if a new combination of two antibiotics, pivmecillinam and amoxicillin/clavulanic acid, can effectively treat complicated urinary tract infections in adults who are switching from intravenous to oral medication.

  Recruiting at 5 sites Phase 3 Lund University · Helsingborg and 4 other locations · NCT05224401

• Using antibiotic-impregnated bone grafts to prevent infections in hip replacements

  This study is testing if using bone grafts soaked in antibiotics can help prevent infections in people getting hip replacements.

  Recruiting Phase 2 University Hospital, Linkoeping · Linköping, Region Östergotland · NCT05169229

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.