Interdisciplinary therapy for obesity management
Official title: Pilot Project on Interdisciplinary Therapy of Obesity and Its Consequences on Body Weight, Quality of Life and Gastrointestinal Parameters
Run by University of Hohenheim · NCT01344525 · Data updated 2026-11-12
This study is testing different weight loss methods, like special diets and surgery, to see how they affect obesity and gut health over three years.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 480 (estimated) |
| Sponsor | University of Hohenheim Academic / other |
| Locations | 3 sites (Heidelberg and 2 other locations) |
| Status | Recruiting |
| Started | May 2009 |
| Main results expected | May 2029 |
| Study ends | May 2029 |
| Registry record updated | October 26, 2018 |
| Trial ID | NCT01344525 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18-65 with a BMI over 30 who are undergoing significant weight loss interventions.
✕Probably not a fit
Patients who do not achieve at least a 10% weight loss after intervention or have insufficient follow-up may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project involves obese individuals who undergo significant interventions, such as a low-calorie formula diet or bariatric surgery, with a focus on substantial weight loss of over 10%. Participants will be monitored for at least three years, with regular follow-ups every six months to assess weight changes, quality of life, and various gastrointestinal parameters. A database and biomaterial bank will be established to analyze the relationship between obesity and gastrointestinal health, comparing outcomes of surgical and non-surgical interventions. The study aims to identify gastrointestinal factors that could predict the success of different obesity treatments.
Why it matters
Potential benefit: If successful, this study could lead to improved treatment strategies for obesity and better long-term outcomes for patients.
How similar studies have gone: Other studies have shown promise in understanding the relationship between obesity and gastrointestinal health, but this specific approach is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adults (18-65 years at time of inclusion) * Obesity defined as BMI \> 30 kg/m2 * Obesity treatment (multidisciplinary life style intervention with LCD or bariatric surgery) resulting in an estimated body weight loss of \>10% of the initial body weight within 6 month Exclusion Criteria: * Body weight loss after intervention \< 10% * Follow-up period \< 1 year or number of consultations within 3 years \< 3
Where it's running
-
University of Heidelberg
Heidelberg, Germany Recruiting -
University of Hohenheim
Stuttgart, Germany Recruiting -
University of Tübingen
Tübingen, Germany Recruiting
Study contacts
- Principal investigator: Stephan C. Bischoff, Prof. Dr. — University of Hohenheim, Institute of Nutritional Medicine
- Study coordinator: Antje Damms-Machado, Dipl. troph.
- Email: antje.machado@uni-hohenheim.de
- Phone: +49 711 451017707
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Fasted versus fed aerobic exercise for weight loss and heart health
This 16-week program will see if doing aerobic exercise before breakfast (fasted) versus after eating helps adults with overweight or obesity lose more weight and improve heart-related measures.
-
Personalized weight-loss medication plan for adults with bipolar disorder
This pilot tests whether matching FDA-approved weight-loss medicines to specific obesity types helps adults aged 18–65 with bipolar disorder lose weight.
-
Efsubaglutide alfa for weight loss after metabolic surgery
This trial will test whether efsubaglutide alfa helps people who remain obese six months after metabolic surgery lose weight and improve obesity-related health problems.
-
Family COMIDA — helping Hispanic families choose healthier foods to prevent and reduce obesity
This program tests family-centered support (parent counseling, weekly phone coaching, monthly group sessions, and child education) to help Hispanic parents/caregivers and their 8–12-year-old children prevent or reduce obesity.
-
Protein supplements with semaglutide and a calorie-restricted diet for weight loss
This will test whether adding daily protein supplements to semaglutide plus a calorie-restricted diet helps adults with overweight or obesity lose more weight, preserve muscle, and reduce weight regain.
-
Probiotic or semaglutide plus diet to reduce body weight
This project will test whether adding a probiotic (Lactobacillus paracasei LC-19) or semaglutide to a calorie-restricted diet helps overweight adults lose weight and improve blood sugar and lipid levels.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.