Individualized pelvic floor rehab added to standard urotherapy and alarm therapy for kids with bedwetting
Official title: Effectiveness of Individualized Pelvic Floor Muscle Rehabilitation in Addition to Standard Urotherapy and Alarm Therapy in Children With Primary Monosymptomatic Nocturnal Enuresis
Run by Hacettepe University · NCT07890194 · Data updated 2026-11-12
This trial tests whether adding personalized pelvic floor muscle training to standard alarm therapy helps reduce dry nights in children aged 5–18 with primary monosymptomatic nocturnal enuresis.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 5 Years to 18 Years |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Hacettepe University Academic / other |
| Locations | 1 site (Ankara, Ankara) |
| Status | Recruiting |
| Started | August 31, 2026 |
| Main results expected | December 20, 2028 |
| Study ends | December 20, 2028 |
| Registry record updated | October 22, 2026 |
| Trial ID | NCT07890194 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Children aged 5–18 with primary monosymptomatic nocturnal enuresis who are recommended alarm therapy as a first-line treatment and do not have cognitive impairment or other excluded conditions.
✕Probably not a fit
Participants without improvement in nocturnal dryness or those who do not respond to pelvic floor training may see no additional benefit beyond standard therapy.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This randomized trial compares two treatment strategies for PMNE in children: standard urotherapy and alarm therapy for all participants, with one group also receiving a 12-week individualized pelvic floor muscle rehabilitation program. Outcomes include the number of dry nights, alarm activations, and changes in pelvic floor muscle function. The study follows ICCS criteria to classify enuresis and aims to identify whether the added rehabilitation provides additional benefit beyond standard nonpharmacological therapies. Enrollment targets children aged 5 to 18 who are recommended alarm therapy as a first-line option, excluding those with cognitive impairment or other identifiable anatomical or neurological causes of enuresis.
Why it matters
Potential benefit: If successful, children may experience more dry nights and improved response to alarm therapy with the addition of pelvic floor muscle rehabilitation.
How similar studies have gone: Prior nonpharmacological approaches for enuresis show mixed results; this study tests a more individualized pelvic floor approach in a randomized setting to determine added value.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of primary monosymptomatic nocturnal enuresis (PMNE) according to the International Children's Continence Society (ICCS) diagnostic criteria. * Age between 5 and 18 years. * Willingness to participate in the study and provision of written informed consent by a parent or legal guardian. * Recommendation of enuresis alarm therapy as a first-line treatment. Exclusion Criteria: * Presence of cognitive or intellectual impairment. * Enuresis attributable to anatomical or neurological causes. * Receipt of nonpharmacological treatment for enuresis, such as standard urotherapy, alarm therapy, pelvic floor muscle training, or electrical stimulation, within the preceding six months.
Where it's running
-
Hacettepe University
Ankara, Ankara, Turkey (Türkiye) Recruiting
Study contacts
- Principal investigator: Canan Seyhan, Ph.D. (c) — Hacettepe University
- Study coordinator: Canan Seyhan, Ph.D. (c)
- Email: cananseyhan@gmail.com
- Phone: +90 532 708 2646
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Bedtime device restriction plus desmopressin for bedwetting in kids
This trial tests whether limiting screen time at night helps desmopressin work better for children with primary monosymptomatic nocturnal enuresis.
-
Exercise Self-Efficacy, Body Composition, and Activity in Men with Low Testosterone
This study tests how confident men on testosterone therapy are at staying active and whether that confidence links body fat and lean mass with how much they exercise.
-
Core muscle function and balance in people with leg amputations
This study tests how leg amputation affects core muscles and balance by comparing muscle thickness on the amputated side, the intact side, and healthy people using ultrasound.
-
Aerobic Exercise and Massage for Painful Bladder Syndrome in Women
This study tests whether adding aerobic exercise and connective tissue massage to patient education helps reduce bladder pain and improve symptoms for women with bladder pain syndrome.
-
High-Intensity Interval Training on a Stationary Bike for Walking and Function Across Different Levels of MS Disability
This study tests a stationary bike HIIT program to see if it improves walking distance, fatigue, balance, strength, endurance, gait speed, and quality of life in people with multiple sclerosis across mild, moderate, and severe disability.
-
Brain-heart axis in adults with type 2 diabetes
This study tests how brain activity and heart regulation relate to metabolic status in adults with type 2 diabetes to understand cognitive and functional health.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.