Improving Walking in Older Adults After Brain Injury

Planning, Reminders and Micro-incentives to Increase Walking After Traumatic Brain Injury in Older Adults

Not applicable Interventional Northeastern University · NCT06222502

This study is testing two different ways to help older adults who have had a mild or moderate brain injury walk more by either giving them planning support and reminders or health tips over 12 weeks.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages40 Years to 80 Years
SexAll
SponsorNortheastern University Academic / other
Locations1 site (Boston, Massachusetts)
Trial IDNCT06222502 on ClinicalTrials.gov

What this trial studies

This research aims to evaluate the effectiveness of two behavioral interventions on increasing walking activity in older adults who have experienced a mild or moderate traumatic brain injury (TBI). Participants will be randomly assigned to either a group that receives planning, reminders, and micro-incentives or a group that receives health education tips. Over a 12-week period, participants will track their walking using a Fit Bit and receive weekly phone calls from study staff. The study will also investigate whether MRI data correlates with physical activity levels.

Who should consider this trial

Good fit: Ideal candidates are older adults aged 40-80 who have suffered a mild or moderate TBI within the last 3 months to 15 years.

Not a fit: Patients who have not experienced a TBI or those who are unable to participate in physical activity due to severe health issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance physical activity levels and overall health in older adults recovering from traumatic brain injuries.

How similar studies have performed: Other studies have shown promising results with behavioral interventions aimed at increasing physical activity in older adults, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

• Suffered a mild or moderate traumatic brain injury within 3 months to 15 years prior to recruitment.

\* TBI history will be assessed using the validated OSU TBI history questionnaire (Attachment 1). TBI severity will be defined as loss of consciousness of 0-30 minutes (mild) or \>30 minutes and \<24 hours (moderate). If no loss of consciousness was reported but post-traumatic amnesia was reported, then this is considered a mild TBI.

If clinical reports from the time of injury are available and Glasgow Coma Scale scores are available, then 13-15 is considered mild and 9-12 moderate. A clinical neurologist will review the de-identified OSU TBI forms for accuracy and confirm TBI severity.

* Men and women of all ethnicities/races and socio-economic status.
* 40-80 years.
* Signed Informed consent.
* Physically fit enough to undergo exercise as screened using the Physical Activity Readiness Questionnaire (PAR-Q) and the cardiovascular section of the Health History \& Demographics Questionnaire. An affirmative response (i.e., \"yes\") to any single item regarding an individual's health status is grounds for the necessary medical clearance before enrollment.
* Normal or corrected-to-normal vision based on the minimal 20/20 standard in order to complete the cognitive tasks (below 20/20 vision).
* Able to speak, read, and write English.
* Ambulatory without pain or the assistance of walking devices.
* Reliable means of transportation (if participating in Boston).
* No diagnosis of a neurological disease.
* No intracerebral brain bleeds.
* Access to a mobile device, laptop or desktop computer with internet access and Bluetooth.

Exclusion Criteria:

* Diagnosis of a severe TBI (loss of consciousness \>24 hours, post-traumatic amnesia \> 7 days of a Glasgow Coma Scale of \<9) or the presentation of skull breach.
* Prior diagnosis of cognitive or physical disability (severe asthma, epilepsy, chronic kidney disease, and dependence upon a wheelchair/walking aid).
* Not fluent in English.
* Undergoing any speech or physical therapy
* Not medically cleared for exercise.
* No history of vasovagal episodes (sudden drops in heart rate, poor perfusion, constant dizziness)
* History of intracerebral brain bleeds or strokes.
* Neurological condition (MS, Parkinson's, Dementia, MCI).
* Current treatment for congestive heart failure, angina, uncontrolled arrhythmia, DVT or other cardiovascular events.
* Myocardial infarction, coronary artery bypass grafting, angioplasty or other cardiac condition in the past year.
* Regular use of an assisted walking device.

Where this trial is running

Boston, Massachusetts

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Traumatic Brain InjuryTBIMild Traumatic Brain InjuryModerate Traumatic Brain InjuryBrain InjuryWalkingExercise
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.