Improving smoking cessation success through sleep and chess training

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to enhance the effectiveness of smoking cessation programs for individuals with tobacco use disorder by integrating cognitive remediation training using chess and improving sleep through high-intensity interval training. Participants will undergo fMRI measurements and sleep monitoring before being assigned to one of four experimental groups that combine these interventions. The study hypothesizes that both chess-based training and sleep enhancement will improve treatment outcomes, either individually or in combination. The approach is designed to be cost-effective and increase patient compliance by utilizing app-based training methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* severe tobacco use disorder (TUD) according to DSM-5
* sufficient ability to communicate with investigators and answer questions in both written and verbal format
* ability to provide fully informed consent and to use self-rating scales
* right-handedness
* HIIT can be performed without the risk of side effect (medical sports check)

Exclusion Criteria:

* severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for mild depression, i.e. F32.0, adjustment disorder and specific phobias) in the last 12 months
* history of brain injury
* severe physical diseases
* common exclusion criteria for MRI (e.g. metal, claustrophobia)
* positive drug screening (opioids, benzodiazepines, barbiturates, cocaine, amphetamines)
* psychotropic medication within the last 14 days
* pregnancy

Where it's running

• Klinik für Abhängiges Verhalten, Zentralinstitut für Seelische Gesundheit
  Mannheim, Baden-Wurttemberg, Germany Recruiting

Study contacts

• Principal investigator: Sabine Vollstädt-Klein, Prof. Dr. — Central Institute of Mental Health, Mannheim
• Study coordinator: Sabine Vollstädt-Klein, Prof. Dr.
• Email: s.vollstaedt-klein@zi-mannheim.de
• Phone: +49-621/1703

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.