Improving meniscal suture healing with marrow venting
Official title: Biological Augmentation Of Meniscal Repair With Marrow Venting: A Randomized Controlled Trial
Run by Ente Ospedaliero Cantonale, Bellinzona · NCT05053646 · Data updated 2026-11-12
This study tests if adding a marrow venting procedure to meniscal tear surgery can help people heal better and faster than with standard repair alone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 16 Years to 50 Years |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | Ente Ospedaliero Cantonale, Bellinzona Academic / other |
| Locations | 2 sites (Lugano and 1 other locations) |
| Status | Recruiting |
| Started | December 29, 2021 |
| Main results expected | October 1, 2030 |
| Study ends | October 1, 2030 |
| Registry record updated | September 11, 2026 |
| Trial ID | NCT05053646 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 18-45 with confirmed suturable monolateral meniscal tears and a BMI between 18.5 and 35.
✕Probably not a fit
Patients with bilateral meniscal tears, significant associated ligament or cartilage injuries, or other serious health conditions may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates whether a marrow venting procedure can enhance the healing of meniscal tears treated with sutures. Meniscal tears are common knee injuries that can lead to pain and functional limitations. The study aims to determine if combining meniscal repair with marrow venting can improve recovery outcomes compared to standard repair alone. Participants will undergo arthroscopic surgery to repair their meniscal tears while also receiving the marrow venting intervention.
Why it matters
Potential benefit: If successful, this approach could lead to better healing rates and improved recovery for patients with meniscal tears.
How similar studies have gone: Previous studies have shown promising results with similar marrow venting techniques, although this specific approach is being tested for the first time in this context.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Arthroscopic confirmed suturable meniscal tears, * Monolateral meniscal tears, * 18-45 years, * BMI\>18,5 and \<35 kg/m2, * Ability to give informed consent by signature. Exclusion Criteria: * Bilateral meniscal tears requiring treatment, * Associated ligament lesions requiring treatment, * Associated cartilage lesions (Outerbridge \> 2), * Knee axis deformities requiring correction * Generalized ligamentous laxity, * Radiographic knee ostheoarthritis, * Other reasons for knee pain, * Pregnant or lactating women, * Serious systemic diseases such as cardiac, hepatic or renal failure, rheumatic diseases, non-compensated diabetic, psychological illnesses, central or peripheral neurological diseases, and autoimmune diseases, * Enrolled in another ongoing clinical trial.
Where it's running
-
Ente Ospedaliero Cantonale
Lugano, Switzerland Recruiting -
Clinica Ars Medica
Lugano, Switzerland Recruiting
Study contacts
- Principal investigator: Christian Candrian, MD — Ente Ospedaliero Cantonale, Bellinzona
- Study coordinator: Christian R Candrian, MD
- Email: RicercaOrtopedia.ORL@eoc.ch
- Phone: +41918117029
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
-
Partial meniscus replacement using Spongioflex®
This study is testing a new type of graft called Spongioflex® to see if it can help younger, active people with meniscus injuries recover better than with traditional methods and avoid future knee problems.
-
Quality of life after open repair for complex abdominal aortic aneurysms
This project will use the SF-36 questionnaire to see how open surgical repair affects quality of life over one year in adults having open surgery for complex abdominal aortic aneurysms.
-
Music to reduce stress during wound dressing
The team will try playing music chosen by hospitalized adults during wound dressing to see if it reduces stress and improves the experience.
-
Using virtual reality to reduce the need for preoperative sedative medication
This trial will try virtual reality to see if it reduces the need for sedative premedication in adults who request medication before elective surgery.
-
Fixing a broken elbow with a metal plate versus non-surgical care in older adults
This test sees if using a metal plate to fix a displaced olecranon fracture helps older adults with low arm demands recover better and regain arm function than non-surgical treatment.
-
Pudendal nerve block versus sacral erector spinae (ESP) block for pain after hemorrhoidectomy
This will test whether the sacral erector spinae (ESP) block gives equal or better pain relief than the pudendal nerve block for adults having elective hemorrhoid surgery.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.