Improving meniscal suture healing with marrow venting
Biological Augmentation Of Meniscal Repair With Marrow Venting: A Randomized Controlled Trial
This study tests if adding a marrow venting procedure to meniscal tear surgery can help people heal better and faster than with standard repair alone.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 80 (estimated) |
| Ages | 16 Years to 50 Years |
| Sex | All |
| Sponsor | Ente Ospedaliero Cantonale, Bellinzona Academic / other |
| Locations | 2 sites (Lugano and 1 other locations) |
| Trial ID | NCT05053646 on ClinicalTrials.gov |
What this trial studies
This study investigates whether a marrow venting procedure can enhance the healing of meniscal tears treated with sutures. Meniscal tears are common knee injuries that can lead to pain and functional limitations. The study aims to determine if combining meniscal repair with marrow venting can improve recovery outcomes compared to standard repair alone. Participants will undergo arthroscopic surgery to repair their meniscal tears while also receiving the marrow venting intervention.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 18-45 with confirmed suturable monolateral meniscal tears and a BMI between 18.5 and 35.
Not a fit: Patients with bilateral meniscal tears, significant associated ligament or cartilage injuries, or other serious health conditions may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to better healing rates and improved recovery for patients with meniscal tears.
How similar studies have performed: Previous studies have shown promising results with similar marrow venting techniques, although this specific approach is being tested for the first time in this context.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Arthroscopic confirmed suturable meniscal tears, * Monolateral meniscal tears, * 18-45 years, * BMI\>18,5 and \<35 kg/m2, * Ability to give informed consent by signature. Exclusion Criteria: * Bilateral meniscal tears requiring treatment, * Associated ligament lesions requiring treatment, * Associated cartilage lesions (Outerbridge \> 2), * Knee axis deformities requiring correction * Generalized ligamentous laxity, * Radiographic knee ostheoarthritis, * Other reasons for knee pain, * Pregnant or lactating women, * Serious systemic diseases such as cardiac, hepatic or renal failure, rheumatic diseases, non-compensated diabetic, psychological illnesses, central or peripheral neurological diseases, and autoimmune diseases, * Enrolled in another ongoing clinical trial.
Where this trial is running
Lugano and 1 other locations
- Ente Ospedaliero Cantonale — Lugano, Switzerland (Recruiting)
- Clinica Ars Medica — Lugano, Switzerland (Recruiting)
Study contacts
- Principal investigator: Christian Candrian, MD — Ente Ospedaliero Cantonale, Bellinzona
- Study coordinator: Christian R Candrian, MD
- Email: RicercaOrtopedia.ORL@eoc.ch
- Phone: +41918117029
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.