Improving cardiac rehabilitation outcomes with mobile case management

Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)

Not applicable Interventional Mayo Clinic · NCT04938661

This study is testing whether doing heart rehab at home, in a clinic, or a mix of both, with or without mobile support, can help people with heart issues feel better and improve their quality of life.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment333 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorMayo Clinic Academic / other
Locations2 sites (Minneapolis, Minnesota and 1 other locations)
Trial IDNCT04938661 on ClinicalTrials.gov

What this trial studies

This research aims to evaluate the effectiveness of cardiac rehabilitation conducted at home, in a clinic, or a combination of both. It employs a single-center, prospective, three-arm, parallel group, randomized controlled trial design. Participants will be randomly assigned to one of three groups: conventional cardiac rehab only, conventional rehab with mobile health (mHealth) support, or remote case management using mHealth alone. The study will track clinical metrics, service utilization, adherence, and quality of life at baseline and approximately three months after intervention, with additional follow-up at 12 months.

Who should consider this trial

Good fit: Ideal candidates include patients with a history of acute myocardial infarction, acute coronary syndrome, stable angina pectoris, percutaneous coronary intervention, or heart failure who have access to a smartphone or computer.

Not a fit: Patients with ventricular assist devices will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could enhance the accessibility and effectiveness of cardiac rehabilitation for patients recovering from heart conditions.

How similar studies have performed: Other studies have shown promise in using mobile health technologies for cardiac rehabilitation, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Own or have reliable access to a smartphone or desktop computer with internet access
* Have an email address
* Patients who have a history of one of the following; acute myocardial infarction/acute coronary syndrome, stable angina pectoris, percutaneous coronary intervention, or heart failure.
* Patients who have undergone a surgical procedure which includes an indication for cardiac rehabilitation (coronary artery bypass surgery, heart valve repair/replacement, or heart transplant)

Exclusion Criteria:

* Patients referred to cardiac rehab with ventricular assist devices.

Where this trial is running

Minneapolis, Minnesota and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Acute Myocardial InfarctionAcute Coronary SyndromeStable Angina PectorisPercutaneous Coronary InterventionHeart FailureCardiac Rehabilitation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.