Clinical trial Recruiting at 10 sites Interventional Ages 18 and up

Improve how patients stick to their treatments with a simple, standard message from healthcare professionals

Official title: Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals: a Stepped-wedge Multicenter Randomized Trial

Run by Assistance Publique - Hôpitaux de Paris · NCT06748118 · Data updated 2026-11-12

A team delivers a brief, three-point message during visits to help adults with chronic illnesses better follow their treatment plan.

More Chronic Disease trials

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment1210 (estimated)
SponsorAssistance Publique - Hôpitaux de Paris
Academic / other
Locations10 sites (Angers, France and 9 other locations)
StatusRecruiting
StartedMarch 18, 2026
Main results expectedMarch 2028
Study endsMarch 2028
Registry record updatedJuly 1, 2026
Trial IDNCT06748118 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults (18+) with chronic illnesses, enrolled in hospital care pathways, affiliated with the French social security system, and able to consent.

Probably not a fit

Patients in whom the standardized message does not change adherence behaviors or who are in periods where adherence is not the primary driver of outcomes may see no benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study tests whether a standardized, three-point message delivered by trained healthcare professionals during routine consultations can boost therapeutic adherence over six months. The approach uses a simple framework focused on adherence levers to prompt behavior change in patients with chronic conditions. The study design follows a stepped wedge approach, allowing sequential implementation across participating sites to assess impact on adherence. Participation involves patient self-report through an adherence questionnaire and ongoing care within formalized pathways. If successful, findings could inform optimized patient management and resource use in chronic care settings.

Why it matters

Potential benefit: If successful, patients may experience improved consistency in taking medications, potentially improving health outcomes.

How similar studies have gone: Previous adherence interventions in chronic care have shown mixed results; this study tests a standardized, doctor-delivered message in a real-world setting.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adult patients (age ≥ 18 years)
* Affiliated to the French social security system
* Followed in hospital for a chronic pathology within a formalized care pathway
* Having signed a consent form to participate in the study.

Exclusion Criteria:

* Patients included in the control period.
* Patients under guardianship.
* Pregnant or breast-feeding patients.
* Patients taking part in research on compliance

Where it's running

  • CHU d'Angers
    Angers, France, France
    Recruiting
  • CH d'Antibes
    Antibes, France, France
    Recruiting
  • Hôpital Corentin Celton
    Issy-les-Moulineaux, France, France
    Recruiting
  • Hôpital de la Conception
    Marseille, France, France
    Recruiting
  • Hôpital La Timone
    Marseille, France, France
    Recruiting
  • CHU de Nantes
    Nantes, France, France
    Recruiting
Show 4 more locations
  • Hôpital européen Georges-Pompidou
    Paris, France, France
    Recruiting
  • Hôpital Bicêtre
    Paris, France, France
    Recruiting
  • CHU de Toulouse
    Toulouse, France, France
    Recruiting
  • CHU de Tours
    Tours, France, France
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.