Improve how patients stick to their treatments with a simple, standard message from healthcare professionals
Official title: Improving Patients' Adherence to Their Chronic Treatments by Implementing a Simple, Standardized and Redundant Message Delivered by Healthcare Professionals: a Stepped-wedge Multicenter Randomized Trial
Run by Assistance Publique - Hôpitaux de Paris · NCT06748118 · Data updated 2026-11-12
A team delivers a brief, three-point message during visits to help adults with chronic illnesses better follow their treatment plan.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 1210 (estimated) |
| Sponsor | Assistance Publique - Hôpitaux de Paris Academic / other |
| Locations | 10 sites (Angers, France and 9 other locations) |
| Status | Recruiting |
| Started | March 18, 2026 |
| Main results expected | March 2028 |
| Study ends | March 2028 |
| Registry record updated | July 1, 2026 |
| Trial ID | NCT06748118 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (18+) with chronic illnesses, enrolled in hospital care pathways, affiliated with the French social security system, and able to consent.
✕Probably not a fit
Patients in whom the standardized message does not change adherence behaviors or who are in periods where adherence is not the primary driver of outcomes may see no benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional study tests whether a standardized, three-point message delivered by trained healthcare professionals during routine consultations can boost therapeutic adherence over six months. The approach uses a simple framework focused on adherence levers to prompt behavior change in patients with chronic conditions. The study design follows a stepped wedge approach, allowing sequential implementation across participating sites to assess impact on adherence. Participation involves patient self-report through an adherence questionnaire and ongoing care within formalized pathways. If successful, findings could inform optimized patient management and resource use in chronic care settings.
Why it matters
Potential benefit: If successful, patients may experience improved consistency in taking medications, potentially improving health outcomes.
How similar studies have gone: Previous adherence interventions in chronic care have shown mixed results; this study tests a standardized, doctor-delivered message in a real-world setting.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients (age ≥ 18 years) * Affiliated to the French social security system * Followed in hospital for a chronic pathology within a formalized care pathway * Having signed a consent form to participate in the study. Exclusion Criteria: * Patients included in the control period. * Patients under guardianship. * Pregnant or breast-feeding patients. * Patients taking part in research on compliance
Where it's running
-
CHU d'Angers
Angers, France, France Recruiting -
CH d'Antibes
Antibes, France, France Recruiting -
Hôpital Corentin Celton
Issy-les-Moulineaux, France, France Recruiting -
Hôpital de la Conception
Marseille, France, France Recruiting -
Hôpital La Timone
Marseille, France, France Recruiting -
CHU de Nantes
Nantes, France, France Recruiting
Show 4 more locations
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Hôpital européen Georges-Pompidou
Paris, France, France Recruiting -
Hôpital Bicêtre
Paris, France, France Recruiting -
CHU de Toulouse
Toulouse, France, France Recruiting -
CHU de Tours
Tours, France, France Recruiting
Study contacts
- Principal investigator: Brigitte SABATIER, Dr — Assistance Publique - Hôpitaux de Paris
- Study coordinator: Tiffany MARTIN
- Email: tiffany.martin@aphp.fr
- Phone: +33 1 44 84 17 92
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.