Impact of pre-existing heart disease on pregnancy outcomes
Maternal and Offspring Outcomes in Pregnant Women With Pre-existing Atherosclerotic Cardiovascular Disease: A Nationwide Mother-Child Cohort Study
This study looks at how having heart disease before pregnancy affects the health of mothers and their babies during and after pregnancy.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 5461222 (estimated) |
| Sex | Female |
| Sponsor | Samsung Medical Center Academic / other |
| Locations | 1 site (Seoul) |
| Trial ID | NCT06406998 on ClinicalTrials.gov |
What this trial studies
This observational study investigates the relationship between maternal pre-existing atherosclerotic cardiovascular disease (ASCVD) and adverse pregnancy outcomes. It aims to assess how maternal cardiovascular health affects both immediate pregnancy complications and long-term health outcomes for offspring. The study utilizes data from women who had live births in Korea over a 14-year period, focusing on the enduring impacts of maternal health on both mothers and their children.
Who should consider this trial
Good fit: Ideal candidates for this study are pregnant women in Korea with a history of atherosclerotic cardiovascular disease.
Not a fit: Patients without pre-existing cardiovascular conditions or those not pregnant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance understanding of how maternal heart health influences pregnancy and offspring outcomes, potentially leading to improved care strategies.
How similar studies have performed: Previous studies have indicated associations between maternal cardiovascular health and pregnancy outcomes, suggesting that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Women with live birth from Korea (between January 1, 2005 to December 31, 2019) Exclusion Criteria: * None
Where this trial is running
Seoul
- Samsung Medical Center — Seoul, South Korea (Recruiting)
Study contacts
- Principal investigator: Ki Hong Choi, MD — Samsung Medical Center
- Study coordinator: Ki Hong Choi
- Email: cardiokh@gmail.com
- Phone: 82-2-3410-3419
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.