Impact of Infertility on the Sexual Sphere in Couples Using Reproductive Help
Official title: A Retrospective and Prospective Study on the Impact of Infertility on the Sexual Sphere in Couples Undergoing Homologous and Heterologous Assisted Reproduction and in Fertile Controls
Run by Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico · NCT07864935 · Data updated 2026-11-12
This study checks how infertility affects sexual well-being in couples undergoing assisted reproduction.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 240 (estimated) |
| Sponsor | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico Academic / other |
| Locations | 1 site (Mirano) |
| Status | Recruiting |
| Started | August 1, 2026 |
| Main results expected | December 31, 2027 |
| Study ends | January 30, 2028 |
| Registry record updated | November 6, 2026 |
| Trial ID | NCT07864935 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal participants are sexually active couples seeking ART or regular care at the clinic, including infertile couples and a control group with prior full-term pregnancies.
✕Probably not a fit
Individuals with conditions that strongly affect sexual function or with psychiatric/depressive conditions may have limited benefit from these questionnaires.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study enrolls heterosexual couples attending the Urology Unit and ART service to examine how infertility relates to sexual function. Both infertile couples and a control group of previously fertile couples will complete validated questionnaires during routine visits. Participants will include both partners who complete tools about general well-being, sexual function, and, for infertile couples, fertility-specific concerns. Data will be collected from couples pursuing homologous or heterologous ART, with analysis planned to compare outcomes between infertile and fertile groups.
Why it matters
Potential benefit: Findings could improve understanding of sexual health needs in couples facing infertility and inform supportive care.
How similar studies have gone: Prior research using validated sexual health questionnaires has shown meaningful associations between infertility and sexual function, supporting the approach of this observational study.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Sexually active (at least 2 intercourses/week) * Patients who have signed the informed consent form Exclusion Criteria: * Conditions that may affect the sexual function (induratio penis plastica, hypogonadism, genital lichen planus, dyspareunia) * Psychiatric/depressive conditions
Where it's running
-
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Mirano, Italy Recruiting
Study contacts
- Study coordinator: Luca Boeri, MD, PhD
- Email: LUCA.BOERI@POLICLINICO.MI.IT
- Phone: +390255034501
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.