Clinical trial Recruiting at 1 site Phase 2 Interventional Ages 18 to 40 Women only

Hyaluronic acid wash to improve pregnancy outcomes in infertile women

Official title: the Effect of Hyaluronic Acid Platelets Rich Plasma on the Endometrial Receptivity and Intracytoplasmic Sperms Injection Outcome

Run by Al-Nahrain University · NCT06937645 · Data updated 2026-11-12

This study tests if a special wash using hyaluronic acid can help improve the chances of pregnancy for women who are having trouble getting pregnant and are undergoing a specific fertility treatment.

More Infertile Patients trials

Quick facts

PhasePhase 2
Study typeInterventional
Ages18 Years to 40 Years
SexWomen only
Enrollment120 (estimated)
SponsorAl-Nahrain University
Academic / other
Locations1 site (AL-Kadimya, Baghdad Governorate)
StatusRecruiting
StartedSeptember 1, 2023
Main results expectedMay 1, 2025
Study endsAugust 1, 2025
Registry record updatedApril 22, 2025
Trial IDNCT06937645 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are infertile females aged 18-40 who are scheduled for a fresh ICSI cycle using a GnRH antagonist protocol.

Probably not a fit

Patients with uterine pathology, poor responders, or endocrine diseases such as thyroid disorders or diabetes may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effect of hyaluronic acid intrauterine wash on endometrial receptivity in infertile women undergoing intracytoplasmic sperm injection (ICSI). The procedure is performed on the day of oocyte retrieval, and the study measures various parameters related to endometrial receptivity, including subendometrial vasculature indices, before and after the intervention. The goal is to determine whether this treatment can enhance the chances of pregnancy outcomes for participants.

Why it matters

Potential benefit: If successful, this approach could improve pregnancy rates for infertile women undergoing ICSI.

How similar studies have gone: While the specific use of hyaluronic acid in this context is novel, similar studies exploring intrauterine treatments have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Infertile females aged 18-40 years.
* Infertile females scheduled for GnRH antagonist protocol of fresh ICSI cycle.
* Females use dual stimulation (GnRH agonist plus Ovetrelle) for ovulation triggering.

Exclusion Criteria:

* Infertile females diagnosed as a poor responder.
* Infertile females diagnosed with uterine pathology.
* Infertile females who are scheduled for a frozen ICSI cycle.
* Infertile females diagnosed with endocrine diseases like thyroid disease, diabetes mellitus, and hyperprolactinemia.
* Infertile females diagnosed with thrombocytopenia.

Where it's running

  • high institute for infertility diagnosis and ARTS
    AL-Kadimya, Baghdad Governorate, Iraq
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.