Hyaluronic acid wash to improve pregnancy outcomes in infertile women
Official title: the Effect of Hyaluronic Acid Platelets Rich Plasma on the Endometrial Receptivity and Intracytoplasmic Sperms Injection Outcome
Run by Al-Nahrain University · NCT06937645 · Data updated 2026-11-12
This study tests if a special wash using hyaluronic acid can help improve the chances of pregnancy for women who are having trouble getting pregnant and are undergoing a specific fertility treatment.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 120 (estimated) |
| Sponsor | Al-Nahrain University Academic / other |
| Locations | 1 site (AL-Kadimya, Baghdad Governorate) |
| Status | Recruiting |
| Started | September 1, 2023 |
| Main results expected | May 1, 2025 |
| Study ends | August 1, 2025 |
| Registry record updated | April 22, 2025 |
| Trial ID | NCT06937645 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are infertile females aged 18-40 who are scheduled for a fresh ICSI cycle using a GnRH antagonist protocol.
✕Probably not a fit
Patients with uterine pathology, poor responders, or endocrine diseases such as thyroid disorders or diabetes may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effect of hyaluronic acid intrauterine wash on endometrial receptivity in infertile women undergoing intracytoplasmic sperm injection (ICSI). The procedure is performed on the day of oocyte retrieval, and the study measures various parameters related to endometrial receptivity, including subendometrial vasculature indices, before and after the intervention. The goal is to determine whether this treatment can enhance the chances of pregnancy outcomes for participants.
Why it matters
Potential benefit: If successful, this approach could improve pregnancy rates for infertile women undergoing ICSI.
How similar studies have gone: While the specific use of hyaluronic acid in this context is novel, similar studies exploring intrauterine treatments have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Infertile females aged 18-40 years. * Infertile females scheduled for GnRH antagonist protocol of fresh ICSI cycle. * Females use dual stimulation (GnRH agonist plus Ovetrelle) for ovulation triggering. Exclusion Criteria: * Infertile females diagnosed as a poor responder. * Infertile females diagnosed with uterine pathology. * Infertile females who are scheduled for a frozen ICSI cycle. * Infertile females diagnosed with endocrine diseases like thyroid disease, diabetes mellitus, and hyperprolactinemia. * Infertile females diagnosed with thrombocytopenia.
Where it's running
-
high institute for infertility diagnosis and ARTS
AL-Kadimya, Baghdad Governorate, Iraq Recruiting
Study contacts
- Study coordinator: ghada bassim raaf, Ph.D.
- Email: ghadaalanssari@yahoo.co.uk
- Phone: +9647714728261
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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Comparing how the uterus expands during hysterosonography in women monitored for fertility
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This test sees if saline infusion sonohysterography (SIS) can detect pelvic adhesions in women aged 18–45 who are experiencing infertility.
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This study is testing if transplanting frozen ovarian tissue can help women who have lost their fertility due to cancer treatments have children again.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.