Immunomodulatory effects of Spirulina Blue Protein capsules in healthy adults
Official title: A Randomized, Double-Blind, Placebo-Controlled Study to Assess the Immunomodulatory Potential and Safety of Spirulina Blue Protein Capsules in Healthy Volunteers
Run by University of Phayao · NCT07733362 · Data updated 2026-11-12
This study tests whether Spirulina Blue Protein capsules can modulate immune function in healthy adults over 12 weeks, compared with a placebo.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 25 Years to 60 Years |
| Sex | All |
| Enrollment | 54 (estimated) |
| Sponsor | University of Phayao Academic / other |
| Locations | 1 site (Phayao, Changwat Phayao) |
| Status | Recruiting |
| Started | August 15, 2026 |
| Main results expected | November 30, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | July 29, 2026 |
| Trial ID | NCT07733362 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Healthy men and women aged 25–60 with BMI 18.5–24.9 kg/m² who consent to participate and comply with study visits.
✕Probably not a fit
Individuals with immune disorders, significant organ disease, or current use of immune-modulating therapies or supplements may not benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is a randomized, double-blind, placebo-controlled, parallel-group trial in healthy adults aged 25–60. Participants will receive either placebo, 200 mg/day SBP, or 1,000 mg/day SBP for 12 weeks. The study will measure immune cell populations (CD4+, CD8+, NK cells), circulating cytokines, and standard safety labs, along with adverse events and tolerability. Primary aim is to see if SBP alters immune function; secondary aims include safety and changes in hematology and biochemistry. The investigation will contribute data on the safety and potential immunomodulatory effects of SBP in humans.
Why it matters
Potential benefit: If successful, SBP could support development of functional foods or nutraceuticals that help support immune health in adults.
How similar studies have gone: Prior preclinical work suggested immunomodulatory activity, but human data are limited; this trial provides controlled human evidence for SBP’s effects.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Healthy male or female adults aged 25-60 years. * Body mass index (BMI) between 18.5 and 24.9 kg/m². * Able and willing to provide written informed consent. * Willing and able to comply with all study procedures and scheduled visits Exclusion Criteria: * History of diseases affecting the immune system or metabolism, including cardiovascular disease, diabetes mellitus, liver disease, kidney disease, autoimmune disorders, or chronic inflammatory diseases. * Abnormal laboratory findings outside the reference range, including complete blood count, liver function tests, or renal function tests. * Current use of medications or dietary supplements that may affect the study outcomes. * Known allergy to Spirulina, algae-containing dietary supplements, or any component of the study capsules. * Pregnant or breastfeeding women.
Where it's running
-
School of Medical Sciences, University of Phayao
Phayao, Changwat Phayao, Thailand Recruiting
Study contacts
- Principal investigator: Chutamas Thepmalee, PhD — School of Medical Sciences, University of Phayao
- Study coordinator: Chutamas Thepmalee, PhD
- Email: th.chutamas@gmail.com
- Phone: +66 81 042 9243
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.