Examining immune cells in children with ADHD
Immunoprofilling of Peripheral Blood Mononuclear Cells in Children With Attention Deficit/Hyperactivity Disorder
First Affiliated Hospital of Zhejiang University · NCT06109337
This study looks at the immune cells in children with ADHD to see how they differ from kids without ADHD and how these differences might relate to their symptoms and brain function.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 100 (estimated) |
| Ages | 6 Years to 12 Years |
| Sex | All |
| Sponsor | First Affiliated Hospital of Zhejiang University (other) |
| Locations | 1 site (Hangzhou, Zhejiang) |
| Trial ID | NCT06109337 on ClinicalTrials.gov |
What this trial studies
This observational study aims to investigate the immune cell landscape of peripheral blood mononuclear cells in children diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD) compared to typically developing controls. It will analyze differences in immune cell subpopulations, protein expression, and signaling pathways using advanced mass spectrometry flow cytometry technology. Additionally, the study will correlate immune function with cognitive assessments and brain imaging results to better understand the relationship between immune profiles and ADHD symptoms.
Who should consider this trial
Good fit: Ideal candidates for this study are children diagnosed with ADHD who have an IQ of 70 or above.
Not a fit: Patients with schizophrenia, mood disorders, autism, or significant physical and nervous system abnormalities may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into the immune mechanisms underlying ADHD, potentially leading to new therapeutic strategies.
How similar studies have performed: While the approach of examining immune profiles in ADHD is relatively novel, similar studies in other conditions have shown promising results.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: Clinical diagnosis of ADHD； Children with an IQ≥70； Both parents are Han； Agree to take venous blood with informed consent； Exclusion Criteria: Schizophrenia, mood disorder, autism, mental retardation； Obvious physical and nervous system abnormalities；
Where this trial is running
Hangzhou, Zhejiang
- Fu Guanghui — Hangzhou, Zhejiang, China (RECRUITING)
Study contacts
- Principal investigator: Hu Guanghui, doctor — Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine
- Study coordinator: Hu Shaohua, doctor
- Email: dorhushaohua@zju.edu.cn
- Phone: 13957162903
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: ADHD, Immune System, Clinical Syndrome