Clinical trial Recruiting at 1 site Observational Ages 6 to 12

Examining immune cells in children with ADHD

Official title: Immunoprofilling of Peripheral Blood Mononuclear Cells in Children With Attention Deficit/Hyperactivity Disorder

Run by First Affiliated Hospital of Zhejiang University · NCT06109337 · Data updated 2026-11-12

This study looks at the immune cells in children with ADHD to see how they differ from kids without ADHD and how these differences might relate to their symptoms and brain function.

Quick facts

Study typeObservational
Ages6 Years to 12 Years
SexAll
Enrollment100 (estimated)
SponsorFirst Affiliated Hospital of Zhejiang University
Academic / other
Locations1 site (Hangzhou, Zhejiang)
StatusRecruiting
StartedDecember 4, 2023
Main results expectedMay 2027
Study endsDecember 2027
Registry record updatedApril 1, 2025
Trial IDNCT06109337 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are children diagnosed with ADHD who have an IQ of 70 or above.

Probably not a fit

Patients with schizophrenia, mood disorders, autism, or significant physical and nervous system abnormalities may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to investigate the immune cell landscape of peripheral blood mononuclear cells in children diagnosed with Attention Deficit/Hyperactivity Disorder (ADHD) compared to typically developing controls. It will analyze differences in immune cell subpopulations, protein expression, and signaling pathways using advanced mass spectrometry flow cytometry technology. Additionally, the study will correlate immune function with cognitive assessments and brain imaging results to better understand the relationship between immune profiles and ADHD symptoms.

Why it matters

Potential benefit: If successful, this study could provide insights into the immune mechanisms underlying ADHD, potentially leading to new therapeutic strategies.

How similar studies have gone: While the approach of examining immune profiles in ADHD is relatively novel, similar studies in other conditions have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Clinical diagnosis of ADHD; Children with an IQ≥70; Both parents are Han; Agree to take venous blood with informed consent;

Exclusion Criteria:

Schizophrenia, mood disorder, autism, mental retardation; Obvious physical and nervous system abnormalities;

Where it's running

  • Fu Guanghui
    Hangzhou, Zhejiang, China
    Recruiting

Study contacts

  • Principal investigator: Hu Guanghui, doctor — Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine
  • Study coordinator: Hu Shaohua, doctor
  • Email: dorhushaohua@zju.edu.cn
  • Phone: 13957162903

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.