Clinical trial Recruiting at 1 site Observational Ages 18 and up

Analyzing immune cells in lung tumors

Official title: Biological Observational Monocentric Study Aimed at Analyzing the Lymphocytic Infiltrate of Lung Tumors

Run by Scientific Institute San Raffaele · NCT06470607 · Data updated 2026-11-12

This study is trying to understand how immune cells behave in lung tumors by collecting samples from patients with non-small cell lung cancer who are having surgery.

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment70 (estimated)
SponsorScientific Institute San Raffaele
Academic / other
Drugs / interventionschemotherapy
Locations1 site (Milan)
StatusRecruiting
StartedJanuary 20, 2023
Main results expectedJanuary 20, 2026
Study endsJanuary 31, 2028
Registry record updatedNovember 29, 2024
Trial IDNCT06470607 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults over 18 years old who are diagnosed with thoracic tumors and are eligible for surgical treatment.

Probably not a fit

Patients who have undergone chemotherapy in the last 6 months, are pregnant or breastfeeding, or have an immunosuppressive condition may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to reconstruct the molecular organization of thoracic tumors, particularly non-small cell lung cancer (NSCLC). It involves collecting clinical data and biological samples, including blood and tumor tissue, from 70 patients diagnosed with thoracic tumors who are candidates for surgical treatment. The study will take place during a single hospital visit, coinciding with the surgical procedure, and will last for a total of three years. The data collected will help in understanding the immune response in lung cancer.

Why it matters

Potential benefit: If successful, this study could enhance our understanding of the immune landscape in lung tumors, potentially leading to improved treatment strategies.

How similar studies have gone: Other studies focusing on the immune response in cancer have shown promising results, indicating that this approach has potential for success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Ability to provide informed consent;
* Men and women over the age of 18;
* Patients candidates for surgical treatment diagnosed with thoracic tumors

Exclusion Criteria:

* Previous chemotherapy for any cancer within the last 6 months;
* Pregnant and/or breastfeeding women;
* Immunosuppressive state (states of immunosuppression or ongoing immunosuppressive/immunomodulatory treatments)

Where it's running

  • Scientific Institute Ospedale San Raffaele
    Milan, Italy
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.