Imagery rescripting at your GP practice
Imagery Rescripting Within Primary Care to Manage Depression: A Single-Case Experimental Design
NA · University of Amsterdam · NCT07362511
This study will see if five sessions of imagery rescripting delivered by trained mental health assistants at a GP practice can reduce depressive symptoms in adults with depression or low self-esteem.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 12 (estimated) |
| Ages | 18 Years to 70 Years |
| Sex | All |
| Sponsor | University of Amsterdam (other) |
| Locations | 1 site (Amsterdam, North Holland) |
| Trial ID | NCT07362511 on ClinicalTrials.gov |
What this trial studies
This study uses a multiple-baseline single-case experimental design to test imagery rescripting delivered in primary care. Participants are randomized to a 2–4 week baseline period, then receive five 45‑minute imagery rescripting sessions over a 10‑week intervention provided by trained mental health assistants at the University of Amsterdam GP practice. Participants complete twice-weekly symptom ratings throughout baseline and treatment (32–36 assessments total), plus five longer questionnaires including 3‑ and 6‑month follow-ups. Outcomes include changes in depressive symptoms, acceptability of the intervention in general practice, and feasibility of delivery by mental health assistants.
Who should consider this trial
Good fit: Adults 18–70 with a main complaint of depressive feelings, a HADS depression score ≥11, ability to read Dutch or English, and willingness to participate are the intended participants.
Not a fit: People with acute suicide risk, suspected primary bipolar disorder, psychosis, substance use disorder, serious neurological problems (such as dementia), or those unable to attend in-person sessions are unlikely to be eligible or to benefit.
Why it matters
Potential benefit: If successful, this could reduce depressive symptoms and make a brief, trauma-focused therapy more accessible through GP-based mental health assistants.
How similar studies have performed: Imagery rescripting has shown benefit in prior psychotherapy studies for depression and trauma-related imagery, but delivering it in primary care by mental health assistants is relatively untested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Main complaint of depressive feelings, as indicated by both the mental health assistant and the patient. * HADS score for the depression subscale ≥ 11. * Ability to understand, read, write and speak Dutch or English. * Age between 18 and 70. * Willingness to participate in the study and treatment. Exclusion Criteria: * Acute suicide risk (BDI-II-item9 score of 3). * If the mental health assistant suspects that the patient may have a primary diagnosis of bipolar disorder, psychosis, substance use disorder, low IQ, or if the patient suffers from serious neurological problems such as dementia, then the patient is not included. There will not be a formal assessment of a primary diagnosis.
Where this trial is running
Amsterdam, North Holland
- UvA Huisartsen — Amsterdam, North Holland, Netherlands (RECRUITING)
Study contacts
- Study coordinator: Lotte Stemerding
- Email: l.e.stemerding@uva.nl
- Phone: 0031614401653
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Major Depressive Diorder, Low Self-Esteem, Mood Disorders, Imagery Rescripting, Depression, Primary care