Condition

Major Depressive Diorder clinical trials and research

• 5Clinical trials
• 5Countries

Newest Major Depressive Diorder clinical trials

All recruiting trials (5)

• Imagery rescripting at your GP practice

  This study will see if five sessions of imagery rescripting delivered by trained mental health assistants at a GP practice can reduce depressive symptoms in adults with depression or low self-esteem.

  Recruiting University of Amsterdam · Amsterdam, North Holland · NCT07362511

• Psilocybin plus cognitive behavioral therapy for depression

  This trial will test whether two doses of psilocybin given alongside cognitive behavioral therapy help adults aged 21–60 with major depressive disorder.

  Recruiting Phase 1/2 University of California, Los Angeles · Los Angeles, California · NCT07281352

• Evaluating deep TMS devices for treating adolescent depression

  This study is testing two different devices to see which one works better for treating depression in teenagers aged 11 to 23.

  Recruiting at 2 sites The First Affiliated Hospital of Shanxi Medical University · Taiyuan, Shanxi and 1 other locations · NCT06728280

• Exploring brain activity changes in depression treatment with rTMS

  This study is testing how a treatment called rTMS changes brain activity in people with major depression to see if it can help improve their mood and reduce the chance of relapse.

  Recruiting Phase 1 Sunnybrook Health Sciences Centre · North York, Ontario and 1 other locations · NCT06719427

• GlobalMinds: a global genetic and health-record database to improve personalized care for people with serious mental illness and dementia

  This project will collect whole-genome data and linked health records from 50,000 adults with major mental illnesses or dementia to see if combining genetic and clinical information can help personalize diagnosis and treatment.

  Recruiting Akrivia Health · Oxford, Oxford · NCT06641726

Related topics

Quick answers

How many Major Depressive Diorder clinical trials are recruiting right now?

5, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 5 countries. The most sites are in China (1 trial), United Kingdom (1 trial), Canada (1 trial), United States (1 trial), Netherlands (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 1: 1, Phase 1/2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

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