Identifying brain markers for chronic low back pain

Characterization of Longitudinal EEG Biomarkers in Chronic Low Back Pain

Not applicable Interventional Stanford University · NCT06025201

This study is testing if brain activity patterns can help predict how chronic low back pain will progress in people who suffer from it.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment130 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorStanford University Academic / other
Locations1 site (Palo Alto, California)
Trial IDNCT06025201 on ClinicalTrials.gov

What this trial studies

This study aims to identify EEG-based biomarkers that can predict the progression of chronic low back pain (CLBP) symptoms. By utilizing various EEG techniques, including resting state and picture viewing, researchers will analyze brain activity patterns in individuals with CLBP. The goal is to enhance the understanding of neural networks associated with pain chronification and improve precision-based treatment approaches. This research addresses the significant gap in effective treatment options for CLBP, which affects a large portion of the adult population globally.

Who should consider this trial

Good fit: Ideal candidates for this study are adults currently diagnosed with chronic low back pain.

Not a fit: Patients with severe psychiatric conditions, current cancer diagnoses, or those involved in personal litigation related to an injury may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to more effective, personalized treatments for patients suffering from chronic low back pain.

How similar studies have performed: While the approach of using EEG to identify biomarkers in chronic pain is promising, it is still relatively novel and has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Current diagnosis of Chronic Low Back Pain

Exclusion Criteria:

* Current diagnosis of cancer
* Severe psychiatric conditions
* Pending personal litigation relating to an injury or receiving workers' compensation benefits
* Being a non-English speaker.

Where this trial is running

Palo Alto, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Chronic Low-back PainHealthy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.