Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Hybrid AI chatbot for financial help in rural cancer care

Official title: SAFE.AI: Developing and Testing an AI-based Hybrid Chatbot for Financial Empowerment in Rural Cancer Care

Run by University of Utah · NCT07410689 · Data updated 2026-11-12

A randomized pilot tests whether a hybrid chatbot provides better financial information and support for rural cancer patients and caregivers than an AI-enabled chatbot.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment60 (estimated)
SponsorUniversity of Utah
Academic / other
Locations1 site (Salt Lake City, Utah)
StatusRecruiting
StartedSeptember 2026
Main results expectedDecember 2027
Study endsDecember 2027
Registry record updatedSeptember 25, 2026
Trial IDNCT07410689 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults 18+ who have cancer or are financially responsible caregivers, reside in the five-state Huntsman catchment area, are rural residents, and can read/write English.

Probably not a fit

Participants who do not experience financial toxicity or who cannot benefit from digital tools may see no personal financial impact.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a randomized, two-arm pilot trial enrolling about 60 participants in rural Utah, Idaho, Wyoming, Montana, and Nevada. Participants are assigned 1:1 to a rule-based/hybrid chatbot or an AI-enabled chatbot to obtain information about insurance, travel costs, and other financial aspects of cancer care. The study uses a community-engaged SAFE toolkit and targets adult cancer patients or financially responsible caregivers who live in rural areas and can read and write in English. The goal is to see which chatbot more effectively delivers clear financial information and resources to ease financial toxicity in rural settings. Outcomes will inform future scalability of proactive financial navigation for rural populations.

Why it matters

Potential benefit: If successful, participants may receive clearer guidance on financial resources and services to reduce out-of-pocket costs and travel-related burdens.

How similar studies have gone: Prior financial-navigation approaches have shown promise, but this is among the first to compare a hybrid chatbot with an AI-enabled chatbot in a rural cancer population.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Adults (18 years and older)
* Cancer patients or financially responsible caregivers of cancer patients who:
* Reside in the Huntsman Cancer Institute's five-state catchment area (Utah, Idaho, Wyoming, Montana, and Nevada),
* Are able to read and write in English, and
* Live in a rural area, defined by endorsement of a residential ZIP code classified as non-metropolitan (RUCA codes 4-10) per the USDA Rural-Urban Commuting Area Codes.

Exclusion Criteria:

* Respondents who do not live within this 5-state region--The SAFE toolkit material was developed for the Huntsman Cancer Institute patient population which serves UT, ID, MT, WY, \& NV
* Respondents who only speak Spanish or other exclusively non-English speaking groups--The large language model for the chatbot will be developed in the English language. As non-English language training for the chatbot is not part of the scope of this study, participants who are unable to read and write in English may not be appropriate. As such, we will not be recruiting participants who only speak Spanish or other exclusively non-English speaking groups. Future studies will include adaptation of the chatbot to other languages.
* Caregivers who are not primarily responsible for the financial aspects of patients' cancer care--The topic of financial hardship of cancer care may be less relevant for caregivers who are not financially involved in care.
* Non-rural dwelling

Where it's running

  • Huntsman Cancer Institute/ University of Utah
    Salt Lake City, Utah, United States
    Recruiting

Study contacts

  • Principal investigator: Djin Tay, PhD, RN — Huntsman Cancer Institute

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.