How the placenta, blood, and urine samples can help us understand preeclampsia and growth problems in pregnancy
Official title: Study of the Physiology of Pre-eclampsia and Vascular Intrauterine Growth Restriction With Constitution of a Biological Collection
Run by Centre Hospitalier Intercommunal Creteil · NCT03626233 · Data updated 2026-11-12
This study collects placenta, blood, and urine samples at delivery from pregnant women to help researchers understand preeclampsia and fetal growth restriction.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 500 (estimated) |
| Sponsor | Centre Hospitalier Intercommunal Creteil Academic / other |
| Locations | 1 site (Créteil) |
| Status | Recruiting |
| Started | August 6, 2018 |
| Main results expected | August 2028 |
| Study ends | August 2028 |
| Registry record updated | June 12, 2026 |
| Trial ID | NCT03626233 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Pregnant women who have or do not have vascular pathology and are willing to participate in sample collection at delivery.
✕Probably not a fit
Participants who do not experience preeclampsia or IUGR or who do not contribute to the sample set may not directly benefit.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This is an observational study that aims to collect biological samples at delivery to study the physiology of preeclampsia and vascular fetal growth restriction. Researchers will gather placental tissue, blood, and urine to build a biological collection. The goal is to improve knowledge of how these placental vascular problems develop and to support future obstetric and neonatal care.
Why it matters
Potential benefit: Better understanding of preeclampsia and IUGR could lead to improved prevention, monitoring, and treatment options for mothers and babies.
How similar studies have gone: Other studies collecting placental and biological samples have contributed to progress in understanding placental vascular diseases, though direct treatments remain limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * pregnant women * With or without vascular pathology Exclusion Criteria: * refusal to participate * multiple pregnancy * major fetal malformation diagnosed during pregnancy follow-up
Where it's running
-
CHi Creteil
Créteil, France Recruiting
Study contacts
- Principal investigator: Edouard Lecarpentier, MD PhD — Chi Creteil
- Study coordinator: Diane REDEL
- Email: diane.redel@chicreteil.fr
- Phone: 145175530
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.