How the body responds to exercise with low oxygen in healthy adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This protocol investigates physiological responses during whole-body and localized exercise combined with hypoxic exposure. It includes cycling, treadmill running, and knee-extension tasks while subjects breathe gas mixtures with reduced oxygen, simulating high-altitude conditions. The study is interventional and involves healthy volunteers aged 18 to 55 with BMI under 30, overseen by the University Hospital of Grenoble and its collaborators at CReSI. Participants must meet safety criteria and provide informed consent, with exclusion for existing cardiorespiratory, metabolic, or neurological disorders. The aim is to characterize how different exercise and oxygen environments affect key physiological parameters in healthy individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Healthy male or female volunteers
* Aged 18-55
* Body Mass Index \<30 kg/m²
* Participants covered by a social security scheme
* Participants capable of signing an informed consent form
* Negative pregnancy test and highly effective contraception for women of childbearing age

Exclusion Criteria:

* Cardiorespiratory, metabolic and neurological disorders, or other conditions assessed during the inclusion consultation that may affect physiological responses to exercise or hypoxia
* Pharmacological treatment taken during the study, other than oral or implantable contraceptive medication for female volunteers of childbearing age

Where it's running

• CReSI (centre de recherche en santé intégrée)
  La Tronche, France Recruiting

Study contacts

• Study coordinator: Samuel Vergès
• Email: sverges@chu-grenoble.fr
• Phone: +33670395773

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.