Clinical trial Recruiting at 1 site Interventional Ages 18 and up

How symptoms, thoughts, and behaviors change week by week during a 7-week online mindfulness program for emotional distress

Official title: Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress

Run by Peking University · NCT07280481 · Data updated 2026-11-12

This trial tests whether a 7-week self-guided online mindfulness program helps people with high emotional distress (such as depression or anxiety) and tracks weekly changes in their emotions, thoughts, and behaviors.

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Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment500 (estimated)
SponsorPeking University
Academic / other
Locations1 site (Beijing)
StatusRecruiting
StartedNovember 16, 2025
Main results expectedApril 28, 2026
Study endsMay 22, 2026
Registry record updatedApril 27, 2026
Trial IDNCT07280481 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults experiencing high emotional distress (Kessler-10 score >21) who do not have prior mindfulness meditation experience and who are not currently at suicidal risk, diagnosed with bipolar disorder or schizophrenia, actively substance dependent, or with severe personal trauma history are the intended participants.

Probably not a fit

People with active self-harm or suicidal risk, diagnosed bipolar disorder or psychosis, current substance abuse, severe trauma history, or those already experienced in mindfulness meditation are unlikely to benefit from this intervention or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional project compares people who begin a 7-week self-guided Mindfulness Intervention for Emotional Distress (iMIED) with a waitlist group. Participants complete short weekly questionnaires about emotions, thoughts, behaviors, and psychological skills before, during, and after the program. Researchers use multi-timepoint network analysis to map how relationships between symptoms and psychological variables change over time and to identify which skills change first and lead to later relief. The design aims to reveal dynamic pathways of change rather than only average symptom reduction.

Why it matters

Potential benefit: If successful, the program could offer an accessible, low-cost online option that reduces emotional distress and pinpoint which psychological skills drive improvement.

How similar studies have gone: Mindfulness-based interventions have shown symptom reductions for some people with depression and anxiety in prior research, but applying intensive weekly network analysis to track dynamic change is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* experiencing emotional distress such as depression or anxiety (Kessler-10 score \> 21)

Exclusion Criteria:

* prior experience with mindfulness meditation
* current self-harm or suicidal risk
* bipolar disorder or schizophrenia
* history of substance abuse
* severe personal trauma history

Where it's running

  • Peking University
    Beijing, China
    Recruiting

Study contacts

  • Principal investigator: Xinghua Liu — School of Psychological and Cognitive Sciences, Peking University
  • Study coordinator: Mo Chen
  • Email: 514100919@qq.com
  • Phone: +86 18950308693

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.