How symptoms, thoughts, and behaviors change week by week during a 7-week online mindfulness program for emotional distress
Official title: Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress
Run by Peking University · NCT07280481 · Data updated 2026-11-12
This trial tests whether a 7-week self-guided online mindfulness program helps people with high emotional distress (such as depression or anxiety) and tracks weekly changes in their emotions, thoughts, and behaviors.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Peking University Academic / other |
| Locations | 1 site (Beijing) |
| Status | Recruiting |
| Started | November 16, 2025 |
| Main results expected | April 28, 2026 |
| Study ends | May 22, 2026 |
| Registry record updated | April 27, 2026 |
| Trial ID | NCT07280481 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults experiencing high emotional distress (Kessler-10 score >21) who do not have prior mindfulness meditation experience and who are not currently at suicidal risk, diagnosed with bipolar disorder or schizophrenia, actively substance dependent, or with severe personal trauma history are the intended participants.
✕Probably not a fit
People with active self-harm or suicidal risk, diagnosed bipolar disorder or psychosis, current substance abuse, severe trauma history, or those already experienced in mindfulness meditation are unlikely to benefit from this intervention or be eligible.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This interventional project compares people who begin a 7-week self-guided Mindfulness Intervention for Emotional Distress (iMIED) with a waitlist group. Participants complete short weekly questionnaires about emotions, thoughts, behaviors, and psychological skills before, during, and after the program. Researchers use multi-timepoint network analysis to map how relationships between symptoms and psychological variables change over time and to identify which skills change first and lead to later relief. The design aims to reveal dynamic pathways of change rather than only average symptom reduction.
Why it matters
Potential benefit: If successful, the program could offer an accessible, low-cost online option that reduces emotional distress and pinpoint which psychological skills drive improvement.
How similar studies have gone: Mindfulness-based interventions have shown symptom reductions for some people with depression and anxiety in prior research, but applying intensive weekly network analysis to track dynamic change is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * experiencing emotional distress such as depression or anxiety (Kessler-10 score \> 21) Exclusion Criteria: * prior experience with mindfulness meditation * current self-harm or suicidal risk * bipolar disorder or schizophrenia * history of substance abuse * severe personal trauma history
Where it's running
-
Peking University
Beijing, China Recruiting
Study contacts
- Principal investigator: Xinghua Liu — School of Psychological and Cognitive Sciences, Peking University
- Study coordinator: Mo Chen
- Email: 514100919@qq.com
- Phone: +86 18950308693
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.