How Saline Infusion Sonohysterography Helps Assess Cesarean Scar Defects

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective, single-center observational study investigates the diagnostic value of saline infusion sonohysterography (SIS) in evaluating cesarean scar incision structure. Researchers compare SIS findings with hysteroscopy, MRI, and conventional ultrasound to assess detection of cesarean scar diverticula, changes in diverticulum size, and the residual myometrial thickness. Patients with prior cesarean delivery who require SIS and have related symptoms are followed after diverticulum reconstruction to monitor symptom improvement and prognosis for up to one year. The goal is to determine how SIS can support clinical decision-making and patient outcomes, potentially informing standardized assessment and surgical planning. Safety and data completeness are considered through well-defined inclusion and exclusion criteria and follow-up.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* More than 6 months after cesarean delivery;
* Presenting with clinical symptoms-including abnormal uterine bleeding, dysmenorrhea, prolonged menstrual spotting, or secondary infertility;
* Requiring saline infusion sonohysterography (SIS) to evaluate the cesarean scar.

Exclusion Criteria:

* Multiple cesarean deliveries;
* Patients contraindicated for saline infusion sonohysterography (SIS), including pregnancy or suspected pregnancy, failure to meet vaginal hygiene criteria, inability to cooperate during the procedure, or suboptimal image quality;
* Cases with incomplete clinical data or lost to follow-up.

Where it's running

• Tang-Du Hospital
  Xi'an, Shaanxi, China Recruiting

Study contacts

• Principal investigator: Li Zhang, MD — The Second Affiliated Hospital of Air Force Military Medical University
• Study coordinator: Li Zhang, MD
• Email: lilyzhang319_20@hotmail.com
• Phone: 86-29-84778860

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.